SMS Mobile Technology for Vaccine Coverage and Acceptance

NCT01663636 | Completed Results

• 2 other identifiers: 12-1144OPP1061430
• Study Type: observational
• Target: 321
• Locations: 1 country
• Sites: 1

Brief Summary

To pilot test a mobile phone SMS (Short Message Service) system that will provide periodical messaging texts to mothers or custodians of infants who come for their first dose vaccines within the first 3 months of life to improve timely immunization coverage, vaccine acceptance and ensure vaccine safety monitoring. The intervention will include a "cloud-based" information system alimented by mobile phone data entry at the health post nurse level, that links child vaccination status and is able to remind parents and nurses of the need for next vaccination appointment and provide a system for reporting of adverse events following immunization in the immediate post-vaccination period.

Conditions

Adherence to Vaccination Schedules

Keywords

vaccines; SMS; mobile phones

Outcome Measures

Primary Outcomes (1)

• Completion of 3 Doses of Pentavalent Vaccine

  Number of children vaccinated with the recommended dose of Pentavalent vaccines according to the age schedule of the National Immunization Program in Guatemala

  8 months of age

Study Arms (2)

SMS Vaccine

Mothers will be sent an SMS message reminding them to come for their scheduled vaccines 1 week prior to the date of 2nd and 3rd doses

Behavioral: SMS message reminding mothers to come for their scheduled vaccines

Usual care

Mothers under usual care will serve as a control

Interventions

SMS message reminding mothers to come for their scheduled vaccines BEHAVIORAL

Reminder

SMS Vaccine

Eligibility Criteria

• Age: 1 Month - 12 Months
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Infants under 12 months of age from Ministry of Health Clinics in Guatemala City

You may qualify if:

• Infants 1-3 months of age coming for their 1 dose of primary vaccines

You may not qualify if:

• Received 1 dose of vaccines, excluding BCG
• No mobile phone with SMS or unable to use SMS at home
• Intent to move from the clinic area in the next 6 months

Sponsors & Collaborators

• University of Colorado, Denver: lead

Study Sites (1)

University del Valle

Guatemala City, 01001, Guatemala

Location

Related Publications (1)

• Domek GJ, Contreras-Roldan IL, O'Leary ST, Bull S, Furniss A, Kempe A, Asturias EJ. SMS text message reminders to improve infant vaccination coverage in Guatemala: A pilot randomized controlled trial. Vaccine. 2016 May 5;34(21):2437-2443. doi: 10.1016/j.vaccine.2016.03.065. Epub 2016 Mar 26.

  PMID: 27026145 DERIVED

Limitations and Caveats

Study was not powered to assess efficacy. SMS texts platform did not have a reporting feature, limiting our ability to confirm message reception. High vaccine visit completion rates made evaluation of an effect challenging.

Results Point of Contact

• Title: Dr. Edwin J. Asturias
• Organization: Center for Global Health, University of Colorado

edwin.asturias@ucdenver.edu

3037246282

Study Officials

• Edwin J Asturias, MD

  University of Colorado School of Medicine

  PRINCIPAL INVESTIGATOR

• Ingrid L Contreras-Roldan, MD

  University del Valle, Guatemala

  STUDY DIRECTOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 8, 2012
• First Posted: August 13, 2012
• Study Start: September 1, 2012
• Primary Completion: June 1, 2014
• Study Completion: June 1, 2015
• Last Updated: December 31, 2018
• Results First Posted: December 31, 2018

Record last verified: 2018-06

Locations

GU (1)