Ultrasound Guided Adductor Canal Block Versus Femoral Nerve Block for Quadriceps Strength and Fall-risk

NCT01655277 | Completed Phase 4

• 1 other identifier: 11-202
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

Our objective was to determine if an ultrasound guided ACB can preserve quadriceps strength, thus minimizing weakness of knee extension compared with ultrasound guided femoral nerve block. Our primary outcome was the percent of maximum voluntary isometric contraction (MVIC) of knee extension preserved at 30 mins after either an ACB or FNB. Secondary outcomes included MVIC of knee extension at 60 min, hip adduction at 30 and 60 mins, and assessment of fall risk with the Berg Balance Scale (BBS) at 30 minutes.

Conditions

Quadriceps Muscle Weakness; Adductor Muscle Weakness; Fall Risk

Outcome Measures

Primary Outcomes (1)

• Percent of maximum voluntary isometric contraction (MVIC) of knee extension preserved at 30 mins after either an ACB or FNB

  At 30 minutes

Secondary Outcomes (4)

• Percent of maximum voluntary isometric contraction (MVIC) of knee extension preserved at 60 mins after either an ACB or FNB

  At 60 minutes

• Percent of maximum voluntary isometric contraction (MVIC) of hip adduction preserved at 30 mins after either an ACB or FNB

  At 30 minutes

• Percent of maximum voluntary isometric contraction (MVIC) of hip adduction preserved at 60 mins after either an ACB or FNB

  At 60 minutes

• Assessment of fall risk with the Berg Balance Scale (BBS) at 30 minutes after the first nerve block.

  At 30 minutes

Study Arms (2)

Adductor Canal block first

EXPERIMENTAL

This arm received an ultrasound guided adductor canal block with 15mL of chloroprocaine 3% followed by motor, sensory and balance assessments. Then the patients received an ultrasound guided femoral nerve block with 15mL of chloroprocaine 3% followed by sensory and motor assessments.

Procedure: Ultrasound Guided Adductor Canal Block; Procedure: Ultrasound Guided Femoral Nerve Block

Femoral nerve block first

EXPERIMENTAL

This arm received an ultrasound guided femoral nerve block with 15mL of chloroprocaine 3% followed by motor, sensory and balance assessments. Then the patients received an ultrasound guided adductor canal block with 15mL of chloroprocaine 3% followed by sensory and motor assessments.

Procedure: Ultrasound Guided Adductor Canal Block; Procedure: Ultrasound Guided Femoral Nerve Block

Interventions

Ultrasound Guided Adductor Canal Block PROCEDURE

Adductor Canal block first; Femoral nerve block first

Ultrasound Guided Femoral Nerve Block PROCEDURE

Adductor Canal block first; Femoral nerve block first

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults (\>18yrs)
• ASA 1-2

You may not qualify if:

• BMI \>30
• Allergy to local anesthetics
• Pre-existing gait disturbance
• Pre-existing neuropathy

Sponsors & Collaborators

• St. Luke's-Roosevelt Hospital Center: lead

Study Sites (1)

St. Luke's Roosevelt Hospital

New York, New York, 10025, United States

Location

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director of Regional Anesthesia

Study Record Dates

• First Submitted: July 30, 2012
• First Posted: August 1, 2012
• Study Start: February 1, 2012
• Primary Completion: June 1, 2012
• Study Completion: June 1, 2012
• Last Updated: August 1, 2012

Record last verified: 2012-07

Locations

US (1)