Trials Sponsors Conditions Drugs Pricing

Conditions

Vertebral Metastasis

Keywords

Female Breast CancerKidney CancerLung CancerProstate CancerVertebral metastasis

Outcome Measures

Primary Outcomes (1)

Time to Any Skeletal Related Event
Time to any skeletal related event most commonly symptomatic recurrence or progression with pain/neurologic impairment with evidence of radiographic progression (median local progression-free survival).
up to 24 months

Secondary Outcomes (2)

Acute Radiation Toxicity
90 days
Late Radiation Toxicity
2 years

Study Arms (1)

Radiation Therapy to Local Spine Metastasis

EXPERIMENTAL

Conformal High Dose Intensity Modulated Radiation Therapy to a single asymptomatic local spine metastasis.

Radiation: Conformal High Dose Intensity Modulated Radiation Therapy

Interventions

Conformal High Dose Intensity Modulated Radiation TherapyRadiation

Conformal High Dose Intensity Modulated Radiation Therapy 14-16Gy single fraction dosing using 6MV photons

Radiation Therapy to Local Spine Metastasis

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Histological confirmation of malignancy (non-small cell lung cancer, breast cancer (hormone refractory), prostate cancer (hormone refractory), lymphoma, renal cell carcinoma, myeloma by either biopsy or cytology of the primary or metastatic lesion.
Patients must have radiological documentation of metastatic disease to the thoracic or lumbar spine including both positron emitted tomography (PET) or nuclear medicine bone scan (NMBS) and Magnetic Resonance Imaging (MRI) within 4 weeks prior to study entry.

Sponsors & Collaborators

Ronald McGarry
Otherlead

Study Sites (1)

University of Kentucky

Lexington, Kentucky, 40536, United States

MeSH Terms

Conditions

Kidney NeoplasmsLung NeoplasmsProstatic Neoplasms

Interventions

Molecular ConformationRadiotherapy, Intensity-Modulated

Condition Hierarchy (Ancestors)

Urologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteNeoplasmsFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesKidney DiseasesUrologic Diseases

Results Point of Contact

Title: Ronal McGarry
Organization: University of Kentucky

Study Officials

Ronald McGarry, M.D.
University of Kentucky
PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee: No
Restrictive Agreement: No

Enrollment

14 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Professor, Radiation Medicine

Study Record Dates

First Submitted

July 17, 2012

First Posted

July 31, 2012

Study Start

December 9, 2009

Actual (reported)

Study Stopped

Conformal High Dose Intensity Modulated Radiation Therapy for Disease to Thoracic and Lumbar Spine

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Results Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (1)

Radiation Therapy to Local Spine Metastasis

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Source record

Documents

Locations

Conformal High Dose Intensity Modulated Radiation Therapy for Disease to Thoracic and Lumbar Spine

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Results Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (1)

Radiation Therapy to Local Spine Metastasis

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Source record

Documents

Locations