NCT01651689

Brief Summary

Hair disorders, expecialy scarring alopecia were diagnosed by scalp biopsy specimens in horizontal and vertical sections.(1-4) Data on hair density in Thais are lacking, although in Asians have more fewer hairs than whites.(5-7)Howevery, previous study from East Asian just had only one study and the data was more differently from West Asian and whites. Then this study was performed to evaluate hair density in Thais, and compared to previous study.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2010

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2010

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

July 25, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 27, 2012

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
Last Updated

July 27, 2012

Status Verified

July 1, 2012

Enrollment Period

2.5 years

First QC Date

July 25, 2012

Last Update Submit

July 25, 2012

Conditions

Alopecia

Keywords

Scalp biopsyHair countVertical sectionHorizontal sectionThais

Study Arms (1)

Scalp biopsy

Subjects are on scadule list for hair transplantation in Siriraj hospital. Scalp biopsy with punch biopsy No.4 Scalp biopsy by punch biopsy No.4 at occipital area was done in subjects who have hair transplantaion.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Thai patients who have alopecia and on scadule for hair transplantation

You may qualify if:

  • Thai
  • Age \>= 18 years
  • Diagnosis alopecia and on list for hair transplantation in Siriraj hospital

You may not qualify if:

  • Alopecia areata or positive hair pulling test
  • Underlying disease : DM, chronic renal failure, chronic liver disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Siriraj hospital

Bangkok, Bangkok, 10700, Thailand

Location

Related Publications (7)

  • Elston DM, McCollough ML, Angeloni VL. Vertical and transverse sections of alopecia biopsy specimens: combining the two to maximize diagnostic yield. J Am Acad Dermatol. 1995 Mar;32(3):454-7. doi: 10.1016/0190-9622(95)90068-3.

    PMID: 7868715BACKGROUND

  • Elston DM, Ferringer T, Dalton S, Fillman E, Tyler W. A comparison of vertical versus transverse sections in the evaluation of alopecia biopsy specimens. J Am Acad Dermatol. 2005 Aug;53(2):267-72. doi: 10.1016/j.jaad.2005.03.007.

    PMID: 16021122BACKGROUND

  • Garcia C, Poletti E. Scalp biopsy specimens: transverse vs vertical sections. Arch Dermatol. 2007 Feb;143(2):268. doi: 10.1001/archderm.143.2.268-a. No abstract available.

    PMID: 17310014BACKGROUND

  • Elston DM. Vertical vs. transverse sections: both are valuable in the evaluation of alopecia. Am J Dermatopathol. 2005 Aug;27(4):353-6. doi: 10.1097/01.dad.0000164602.10908.92. No abstract available.

    PMID: 16121061BACKGROUND

  • Sperling LC. Hair density in African Americans. Arch Dermatol. 1999 Jun;135(6):656-8. doi: 10.1001/archderm.135.6.656.

    PMID: 10376692BACKGROUND

  • Lee HJ, Ha SJ, Lee JH, Kim JW, Kim HO, Whiting DA. Hair counts from scalp biopsy specimens in Asians. J Am Acad Dermatol. 2002 Feb;46(2):218-21. doi: 10.1067/mjd.2002.119558.

    PMID: 11807433BACKGROUND

  • Aslani FS, Dastgheib L, Banihashemi BM. Hair counts in scalp biopsy of males and females with androgenetic alopecia compared with normal subjects. J Cutan Pathol. 2009 Jul;36(7):734-9. doi: 10.1111/j.1600-0560.2008.01149.x.

    PMID: 19519605BACKGROUND

Biospecimen

Retention: SAMPLES WITHOUT DNA

scalp biopsy specimen

MeSH Terms

Conditions

Alopecia

Condition Hierarchy (Ancestors)

HypotrichosisHair DiseasesSkin DiseasesSkin and Connective Tissue DiseasesPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Officials

  • Rattapon Thuangtong, MD

    Department of Dermatology, Siriraj hospital, Faculty of Medicine, Mahidol University, Thailand

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

July 25, 2012

First Posted

July 27, 2012

Study Start

October 1, 2010

Primary Completion

April 1, 2013

Study Completion

May 1, 2013

Last Updated

July 27, 2012

Record last verified: 2012-07

Locations

TH(1)