Cognitive Training for Post Traumatic Stress Disorder: Effects on Cognitive, Emotional, and Brain Function
Cognitive Training for PTSD: Effects on Cognitive, Emotional, and Brain Function
1 other identifier
interventional
40
1 country
1
Brief Summary
The purpose of this pilot study is to determine the effects of computer-based training in executive functioning compared to word games on cognitive and emotional aspects of combat-related PTSD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jul 2012
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2012
CompletedFirst Submitted
Initial submission to the registry
July 17, 2012
CompletedFirst Posted
Study publicly available on registry
July 19, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2015
CompletedDecember 8, 2014
December 1, 2014
3 years
July 17, 2012
December 4, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Neural activity in prefrontal regions during cognitive and emotional processing measured by functional magnetic resonance imaging.
change from baseline to after 6 weeks of training
Secondary Outcomes (1)
Cognitive functioning as measured by neuropsychological assessment.
change from baseline to after 6 weeks of training
Other Outcomes (1)
Clinical PTSD symptoms as measured by the Clinician Administered PTSD Scale (CAPS).
change from baseline to after 6 weeks of training
Study Arms (2)
Executive function training
EXPERIMENTALExecutive function training
Word game training
PLACEBO COMPARATORComputer-based training in tasks related to verbal processing.
Interventions
Computer-based training in executive functions, administered via www.lumosity.com website.
Eligibility Criteria
You may qualify if:
- combat veterans who served in Operation Iraqi Freedom, Operation Enduring Freedom, or Operation New Dawn
You may not qualify if:
- enrolled in other active treatment protocols
- current substance abuse or dependence
- current suicidal ideation
- diagnosis of a neurological disorder
- history of moderate to severe traumatic brain injury
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Missouri, Kansas Citylead
- University of Kansascollaborator
Study Sites (1)
Univesity of Missouri - Kansas City
Kansas City, Missouri, 64110, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Robin Aupperle, PhD
University of Missouri, Kansas City
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
July 17, 2012
First Posted
July 19, 2012
Study Start
July 1, 2012
Primary Completion
July 1, 2015
Study Completion
July 1, 2015
Last Updated
December 8, 2014
Record last verified: 2014-12