CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions
1 other identifier
observational
N/A
1 country
1
Brief Summary
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 17, 2012
CompletedFirst Posted
Study publicly available on registry
July 19, 2012
CompletedJuly 19, 2012
July 1, 2012
July 17, 2012
July 18, 2012
Conditions
Outcome Measures
Primary Outcomes (1)
Serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
Study Arms (3)
authoimmıne thyroiditis and habitual abortus
authoimmune thyroiditis
healthy controls
Eligibility Criteria
Endocrinology Outpatient Clinic
You may qualify if:
- non-pregnant women with euthyroid autoimmune thyroiditis and a history of first trimester recurrent spontaneous abortions
You may not qualify if:
- \) presence of acute or chronic systemic diseases; 2) other autoimmune diseases; 3) pregnancy and lactation over the previous 6 months; 4) evidence of infectious diseases in the last 3 months; 5) treatment with drugs known to interfere with cytokine release, such as corticosteroids, immunosuppressors, or nonsteroidal antiinflammatory drugs, amiodarone, and lithium; 6) clinical history of hyperthyroidism and/or the presence of anti-TSH receptor antibodies.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ankara Education and Research Hospital
Ankara, 06340, Turkey (Türkiye)
Related Publications (1)
Aktas A, Berberoglu Z, Fidan Y, Yazici AC, Koc G, Aral Y, Ademoglu E, Bekdemir H, Alphan Z. Higher levels of circulating CXCL-9 and CXCL-11 in euthyroid women with autoimmune thyroiditis and recurrent spontaneous abortions. Gynecol Endocrinol. 2014 Feb;30(2):157-60. doi: 10.3109/09513590.2013.871514. Epub 2013 Dec 19.
PMID: 24351073DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER GOV
Study Record Dates
First Submitted
July 17, 2012
First Posted
July 19, 2012
Last Updated
July 19, 2012
Record last verified: 2012-07