Water Exercise and Vascular Function in Elderly

NCT01642654 | Completed DMC

• 1 other identifier: yula01
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Objectives: The purpose of this research was to assess modifications caused by a concurrent water exercise program on plasma nitrite (NO3), cerebral vascular resistance and cholesterol in the elderly and analyze the correlations between these variables after intervention. Methods The sample was composed of 40 women mean age 69,21 ±5,27 years old, divided into an intervention (WG) and control group (CG). It was to measure nitrite concentration (NO3) by the Griess reaction; internal cerebral arteries were assessed by Doppler ultrasound to determine the resistivity index and Cholesterol was determined using the colorimetric enzymatic method and test kit. Intervention with water exercise program consisted of three weekly sessions for 16 weeks.

Conditions

Elderly Women

Outcome Measures

Primary Outcomes (1)

• Determining modifications caused by this program on plasma nitrite concentration (NO3).

  For NO analysis, serum was separated from the erythrocyte mass. The material was centrifuged in a SIGMA 4k15 centrifuge at 3500 rpm and 18° for 10 minutes (LANEX laboratory- UFPI); the serum was then pipetted and frozen at 80° for evaluation after retesting (16 weeks). NO production was determined based on NO3 in the supernatant of cultured cells, an indirect measurement of NO synthesis.

  16 weeks

Secondary Outcomes (1)

• Cerebral artery assessment

  16 weeks

Study Arms (2)

Control

ACTIVE COMPARATOR

Other: Educational lectures

Treatment

EXPERIMENTAL

Other: Exercise

Interventions

Exercise OTHER

The WG was submitted to a 16-week WEP, with combined aerobic and resistance exercises in three weekly sessions. Water temperature was approximately 30º C with an average ambient temperature of 34° C. The pool had water levels ranging between 1,20 and 1,40 meters deep.

Treatment

Educational lectures OTHER

Educational lectures

Control

Eligibility Criteria

• Age: 60 Years - 80 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• older than 60 and lass than 80 years age;
• the elderly should be independent in their ADLs;
• be considered able for medical evaluation to participate in the intervention and testing protocols;
• still not be participating in regular systematized physical activity for at least six months.

You may not qualify if:

• subjects with any form of transmittable or uncontrolled disease or insulin-dependent hypertensive;
• unable to perform functional autonomy tests;
• women undergo hormonal replacement therapy

Sponsors & Collaborators

• Universidade Federal do Rio Grande do Norte: lead

Study Sites (1)

Universidade Estadual do Piauí

Teresina, Piauí, Brazil

Location

Related Publications (1)

• Cress ME, Buchner DM, Prohaska T, Rimmer J, Brown M, Macera C, Dipietro L, Chodzko-Zajko W. Best practices for physical activity programs and behavior counseling in older adult populations. J Aging Phys Act. 2005 Jan;13(1):61-74. doi: 10.1123/japa.13.1.61.

  PMID: 15677836 RESULT

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Arméle Dornelas

  Universidade Federal de Pernambuco

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Msc

Study Record Dates

• First Submitted: July 10, 2012
• First Posted: July 17, 2012
• Study Start: May 1, 2010
• Primary Completion: September 1, 2010
• Study Completion: September 1, 2010
• Last Updated: July 17, 2012

Record last verified: 2012-03

Locations

BR (1)