Effects of Secondhand Smoke on Flight Attendant Health

NCT01639235 | Completed

• 3 other identifiers: 14-13934FAMRI146312
• Study Type: observational
• Target: 592
• Locations: 1 country
• Sites: 1

Brief Summary

This is a study on a population of flight attendants who were exposed to occupational secondhand tobacco smoke (SHS). This research will examine associations between flight attendant SHS exposure and development of respiratory illnesses, reproductive problems, and cardiovascular diseases.

Conditions

Cardiopulmonary Disease

Keywords

Secondhand Smoke; Flight Attendants; Lung function; Cardiac function; Reproductive health

Outcome Measures

Primary Outcomes (1)

• Characterize the long-term effects of SHS on lung and cardiovascular function in pre-ban flight attendants

  A spirometry test is performed by the Clinical Research Coordinator to establish the lung function of the flight attendant participant and medical assistants from the cardiovascular care clinic administer a 12-lead non-invasive electrocardiogram.

  25 minutes

Secondary Outcomes (3)

• Clinical Examination

  30 min

• Characterize the long term effects of prolonged flight time and SHS on reproductive health

  10 minutes

• Characterize the biomarkers of SHS exposure

  10 minutes

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This is a cross-sectional observational study of flight attendants exposed to secondhand tobacco smoke.

You may qualify if:

• Never smoker flight attendants who began working for airlines before the smoking ban on aircrafts went into effect. Never smoker is defined as those with history of tobacco use of less than 100 cigarettes in their lifetime.
• SHS exposure for at least 1 year while working with the airlines.

You may not qualify if:

• Less than 1 year of occupational exposure to SHS
• Smoking more than 100 cigarettes over a lifetime

Sponsors & Collaborators

• University of California, San Francisco: lead
• Flight Attendant Medical Research Institute: collaborator

Study Sites (1)

University of California, San Francisco

San Francisco, California, 94143, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

There is an optional blood draw blood portion to the research study. A sample is collected from the interested flight attendant. The majority of the sample is processed and stored in the FAMRI biorepository for future research purposes to identify biomarkers of cardiovascular risk and secondhand smoke. The remainder of the sample is analyzed for the flight attendant. A lipid profile is sent to the flight attendant participant.

MeSH Terms

Conditions

Pulmonary Heart Disease

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Officials

• Rita Redberg, MD

  University of California, San Francisco

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 9, 2012
• First Posted: July 12, 2012
• Study Start: January 31, 2005
• Primary Completion: December 31, 2020
• Study Completion: December 31, 2020
• Last Updated: January 28, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)