Development of Method of Fructose Identification in Urine to Detect the Viral Infection

NCT01638312 | Completed Results DMC

• 1 other identifier: KMUH-IRB-20110188
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this research is the attempt to implement a new research method based on modern electrochemistry successes, in particular the development of the polarographic method of fructose and fructose diphosphate identification and its implementation to detect the viral infection in early stage. There will be 20 samples from the HIV-infected patients and 30 samples from the heath controls. The study will collect 10ml urine and examined fructose and fructose-diphosphate using the polarographic method.

Conditions

Human Immunodeficiency Virus

Keywords

HIV, fructose

Outcome Measures

Primary Outcomes (1)

• Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform

  This detection technique, after a viral infection caused by the use of cell pathological changes and urine metabolic waste - fructose concentration, derivatives.Health News voltage changes to detect viral pathogens of activity and virulence. Because viral infection caused by the voltage change has its typical, So you can use voltage measurements to calibrate the presence and activity of a viral infection. 1.How to interpretation the data The gap between values on X-axis is σ, and 50 is a reference to the center position. For example, the sample maybe contain with HIV virus if σ≧10 units. σ≧10 abnormal positive (+) σ\<10 normal negative (-)

  Participants provided urine samples once

Study Arms (1)

HIV infection patient and health people

The study does not have intervention

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

the person who has HIV infection

You may qualify if:

• HIV infection

You may not qualify if:

• who are in highly active antiretroviral therapy(HARRT) therapy

Sponsors & Collaborators

• Kaohsiung Medical University Chung-Ho Memorial Hospital: lead

Study Sites (1)

Tropical Medicine Center, Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung, Taiwan, 807, Taiwan

Location

Biospecimen

Retention: NONE RETAINED

urine

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Results Point of Contact

• Title: JihJin Tsai, MD
• Organization: Kaohsiung Medical University Chung-Ho Memorial Hospital

jijits@cc.kmu.edu.tw

886-7-3121101

Study Officials

• JihJin Tsai, MD

  The Medicines Company

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 20, 2012
• First Posted: July 11, 2012
• Study Start: June 1, 2011
• Primary Completion: May 1, 2013
• Study Completion: May 1, 2013
• Last Updated: October 5, 2015
• Results First Posted: October 5, 2015

Record last verified: 2012-09

Locations

TW (1)