NCT01635699

Brief Summary

The purpose of this study is to determine the possible effects of uvulopalatopharngoplasty (UPPP) -which is a a therapy used on patients with Obstructive sleep apnea syndrome (OSAS- on oxidative damage.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2008

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
2.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2011

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

July 4, 2012

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 9, 2012

Completed
Last Updated

July 9, 2012

Status Verified

July 1, 2012

Enrollment Period

Same day

First QC Date

July 4, 2012

Last Update Submit

July 6, 2012

Conditions

Sleep Apnea, Obstructive

Keywords

DNA oxidationobstructive sleep apnealipid peroxidationoxidative stresses

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea syndrome (OSAS) at the otolaryngology department of our hospital in Erzurum, Turkey.

You may qualify if:

  • Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea syndrome (OSAS)

You may not qualify if:

  • Anormal nasopharyngeal computed tomography, chronic diseases such as diabetes mellitus, hypertension etc.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Erzurum Regional Educational Researh Hospital

Erzurum, Erzurum, 25000, Turkey (Türkiye)

Location

Related Publications (1)

  • Bakan E, Fidan V, Alp HH, Baygutalp NK, Cokluk E. Effect of Modified Fujita Technique Uvulopalatoplasty on Oxidative DNA Damage Levels in Patients With Obstructive Sleep Apnea Syndrome. J Craniofac Surg. 2015 Jul;26(5):e392-6. doi: 10.1097/SCS.0000000000001870.

    PMID: 26163849DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

serum, whole blood

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • vural fidan, operating surgeon doctor

    eskisehir yunus emre state hospital (still works here)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
operating surgeon doctor

Study Record Dates

First Submitted

July 4, 2012

First Posted

July 9, 2012

Study Start

June 1, 2008

Primary Completion

June 1, 2008

Study Completion

March 1, 2011

Last Updated

July 9, 2012

Record last verified: 2012-07

Locations

TU(1)