Performance-based Reinforcement to Enhance Cognitive Remediation Therapy
Pilot Study of Performance-based Reinforcement to Enhance Cognitive Remediation Therapy for Substance Users
2 other identifiers
interventional
40
1 country
1
Brief Summary
The purpose of this study is to investigate whether monetary reinforcement for performance will enhance the effects of cognitive remediation therapy for substance users seeking treatment at an outpatient facility.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Sep 2012
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 27, 2012
CompletedFirst Posted
Study publicly available on registry
July 4, 2012
CompletedStudy Start
First participant enrolled
September 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2014
CompletedMarch 9, 2020
March 1, 2020
2.2 years
June 27, 2012
March 4, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Improvement in performance scores on computerized cognitive remediation tasks
Performance scores on various computerized cognitive remediation tasks will be measured repeatedly during the 4 week study. These scores include "time to completion", "number of errors", "number of words correctly recalled", and "percentage of task completed"
4 weeks
Secondary Outcomes (1)
Improved cognitive function on neuropsychological tests
4 weeks
Study Arms (2)
CRT-S
ACTIVE COMPARATORCognitive Remediation Therapy - Standard
CRT-CM
EXPERIMENTALCognitive Remediation Therapy plus Contingency Management
Interventions
Computerized cognitive remediation therapy provided three times per week for four weeks
Standard cognitive remediation therapy plus monetary incentives based on performance provided three times per week for four weeks.
Eligibility Criteria
You may qualify if:
- to 60 years old
- Primary Alcohol and/or Cocaine Abuse/Dependence Diagnosis
- Abstinence from all drugs/alcohol for 30 days
- Mild cognitive impairment
- Sufficiently stable and plan to commit to 4 weeks of outpatient treatment
- Fluent in English and 6th grade reading ability
You may not qualify if:
- Severe cognitive impairment indicative of dementia
- Untreated bipolar or psychotic disorder
- Have current legal case pending such that incarceration during 4-week study is likely
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Yale Universitylead
- National Institute on Drug Abuse (NIDA)collaborator
Study Sites (1)
Substance Abuse Treatment Unit
New Haven, Connecticut, 06511, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Brian D Kiluk, PhD
Yale University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 27, 2012
First Posted
July 4, 2012
Study Start
September 1, 2012
Primary Completion
December 1, 2014
Study Completion
December 1, 2014
Last Updated
March 9, 2020
Record last verified: 2020-03