NCT01632774

Brief Summary

Aortic injuries after blunt thoracic trauma are compared to the great incidence of accidents relatively rare, but potentially serious leading to death at scene in most of the cases. The study was undertaken to delineate mortality and its risk factors on three different levels (pre-hospital, in-hospital and overall). Between 1990 and 2003, all consecutive patients and victims with traumatic aortic rupture were retrospectively analyzed by reviewing hospital and autopsy records.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
85

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 1990

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1990

Completed
13.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2003

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2003

Completed
8.6 years until next milestone

First Submitted

Initial submission to the registry

June 28, 2012

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 3, 2012

Completed
Last Updated

July 3, 2012

Status Verified

June 1, 2012

Enrollment Period

13.9 years

First QC Date

June 28, 2012

Last Update Submit

July 2, 2012

Conditions

Aortic Rupture

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Hospitalized patients Patients who died at the scene

You may qualify if:

  • During the study period of 14 years (January 1990 to December 2003), all consecutive cases with traumatic rupture of the thoracic aorta being reported in the greater area of Zurich with about one million inhabitants were included in the present study

You may not qualify if:

  • Non-traumatic aortic rupture
  • Non-traumatic aortic dissection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Zurich, Division of Internal Medicine

Zurich, Canton of Zurich, 8091, Switzerland

Location

Related Publications (1)

  • Franzen D, Genoni M. Analysis of risk factors for death after blunt traumatic rupture of the thoracic aorta. Emerg Med J. 2015 Feb;32(2):124-9. doi: 10.1136/emermed-2013-202639. Epub 2013 Sep 4.

    PMID: 24005640DERIVED

MeSH Terms

Conditions

Aortic Rupture

Condition Hierarchy (Ancestors)

Aneurysm, RupturedAneurysmVascular DiseasesCardiovascular DiseasesAortic AneurysmAortic DiseasesRuptureWounds and Injuries

Study Officials

  • Daniel Franzen, MD

    University Hospital Zurich, Division of Internal Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 28, 2012

First Posted

July 3, 2012

Study Start

January 1, 1990

Primary Completion

December 1, 2003

Study Completion

December 1, 2003

Last Updated

July 3, 2012

Record last verified: 2012-06

Locations

CH(1)