The Autonomic Nervous System State and Response to Different Stimuli Among Patients Post Stroke: A Follow-up Study

NCT01632410 | Unknown

• 1 other identifier: TASMAC-12-NB-0227-12-CTIL
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The study describes the autonomic control system function in subjects post stroke in comparison with healthy subjects. Aims: To describe the Autonomic hart rate control system function in post stroke subjects in different rehabilitation levels in comparison with healthy subjects. To examine the reflective reaction of the autonomic control system as reflected in the heart rate variability to stimulations subjects in different rehabilitation levels in comparison with healthy subjects. To examine the autonomic control system reaction as reflected in the heart rate variability to physical and cognitive action subjects in different rehabilitation levels in comparison with healthy subjects.

Conditions

Stroke

Keywords

autonomic nerve system; post stroke; focus of study: to describe the autonomic nerve system function post stroke; autonomic nervous system

Outcome Measures

Primary Outcomes (1)

• RMSSD change

  The root mean square successive difference (RMSSD) in heart period series is a time domain measure of heart period variability. we will follow up the change in RMSSD at 1st and 3rd month post stroke

  3 month post stroke

Secondary Outcomes (2)

• 6mwt

  3 month post stroke

• Patient's characteristics

  3 month post stroke

Study Arms (5)

Study group 1

Post hemispheral ischemic stroke cognitively intact. Exclusion: Subjects with severe visual or hearing impairments, stroke location brain steam. The group will be divided in to 4 goups acording to stroke specific location as demonstrated in MRI.

Control

Control: Healthy subjects resemble in age and sex

Study -3

As explained the subjects will be divided into 4 groups acording to the stroke location. this is in order to evaluat the relationship between location and autonomic responed.

Stydy -2

As explained the subjects will be divided into 4 groups acording to the stroke location. this is in order to evaluat the relationship between location and autonomic responed.

Stydy- 4

As explained the subjects will be divided into 4 groups acording to the stroke location. this is in order to evaluat the relationship between location and autonomic responed.

Eligibility Criteria

• Age: 40 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Post hemispheral ischemic stroke cognitively intact.

You may qualify if:

• Post hemispheral ischemic stroke cognitively intact.

You may not qualify if:

• Subjects with severe visual or hearing impairments, stroke location brain steam.

Sponsors & Collaborators

• Tel-Aviv Sourasky Medical Center: lead

Study Sites (1)

Tel Aviv Souraski Medical Center Neurology department

Tel Aviv, Israel

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Nathan Borshtin, Prof.

  Tel Aviv Suraski medical center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Natan Borshtain, prof.

CONTACT

972-3-6973159

Noa Raphaely Beer, Mrs.

CONTACT

972-52-8898918; raphaelybeer@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 20, 2012
• First Posted: July 3, 2012
• Study Start: July 1, 2012
• Primary Completion: November 1, 2012
• Study Completion: December 1, 2013
• Last Updated: July 3, 2012

Record last verified: 2012-06

Locations

IL (1)