NCT01628614

Brief Summary

This is an observational study and will evaluate IOP reduction in newly diagnosed patients with POAG or OHT. All care (including treatment and diagnostic procedures) provided is at the discretion of the participating physicians according to their clinical judgment and the local standard of medical care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,812

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2010

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2010

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2011

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

June 25, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 27, 2012

Completed
2 months until next milestone

Results Posted

Study results publicly available

September 5, 2012

Completed
Last Updated

September 5, 2012

Status Verified

August 1, 2012

Enrollment Period

8 months

First QC Date

June 25, 2012

Results QC Date

August 2, 2012

Last Update Submit

August 2, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percentage of Patients With a Reduction in Intraocular Pressure (IOP) ≥ 5mmHg From Baseline

    Percentage of patients with a reduction in IOP≥5 mmHg from baseline. IOP is a measurement of the fluid pressure inside the eye. The minimum reduction of 5 mmHg was evaluated in the eye with the highest pressure at the baseline visit.

    Baseline, 14 Weeks

Secondary Outcomes (2)

  • Percentage of Patients With an IOP Reduction ≥10% From Baseline

    Baseline, 14 Weeks

  • Percentage of Patients With an IOP Reduction ≥20% From Baseline

    Baseline, 14 Weeks

Study Arms (1)

POAG or OHT

Patients with POAG or OHT. All care (including treatment and diagnostic procedures) provided is at the discretion of the participating physicians according to their clinical judgment and the local standard of medical care.

Other: Standard of Care

Interventions

Patients with POAG or OHT. All care (including treatment and diagnostic procedures) provided is at the discretion of the participating physicians according to their clinical judgment and the local standard of medical care.

POAG or OHT

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with primary open angle glaucoma or ocular hypertension

You may qualify if:

  • Newly diagnosed with primary open angle glaucoma or ocular hypertension

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Unknown Facility

Barcelona, Spain

Location

MeSH Terms

Conditions

Glaucoma, Open-AngleOcular Hypertension

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

GlaucomaEye Diseases

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Results Point of Contact

Title
Vice President Medical Affairs,
Organization
Allergan, Inc

Study Officials

  • Medical Director

    Allergan

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 25, 2012

First Posted

June 27, 2012

Study Start

November 1, 2010

Primary Completion

July 1, 2011

Study Completion

July 1, 2011

Last Updated

September 5, 2012

Results First Posted

September 5, 2012

Record last verified: 2012-08

Locations