NCT01624415

Brief Summary

Humans attain binocular vision from the two retinal images of both eyes through a series of sensory and motor processes that culminate in the perception of stereoscopic depth. Looking at a scene creates two slightly different images on the retinas which is due to the eyes' different positions on the head. This so called binocular disparity provides information to calculate depth and therefore enables stereopsis. Physiologically the two retinal images are superimposed and merge into one stereoscopic image. If one image is presented to one eye in an experimental setting, and a completely different image is presented to the other eye, the investigators visual system, analogous to diplopic vision, is not able to fuse these image stimuli. Instead, a phenomenon called binocular rivalry occurs. Here, both images are seen alternating and the brain can switch back and forth between these images. The aim of the present study is to investigate the effects of objective changes to image quality on the investigators subjective stereoscopic perception. This psychophysiological testing is done by looking at different images and thereafter by subjective grading of the image quality. The investigators hypothesize that overlapping image modifications occurring in both eyes are detected immediately, but changes, that are rotated by 90 degrees against each other, should be suppressed and result in one stereoscopic image, reduced in image quality. Whether this also accounts for more detailed images, such as reading cards, is questionable.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jun 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2012

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

June 18, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 20, 2012

Completed
Last Updated

July 2, 2012

Status Verified

June 1, 2012

Enrollment Period

Same day

First QC Date

June 18, 2012

Last Update Submit

June 28, 2012

Conditions

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

The participants will be selected by the Department of Clinical Pharmacology healthy subjects, male and female, 18-35 years

You may qualify if:

  • Men and women aged between 18 and 35 years, nonsmokers
  • Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
  • Normal ophthalmic findings, emmetropia or ≤ 1 diopter

You may not qualify if:

  • Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
  • Treatment in the previous 3 weeks with any drug (except oral contraceptives)
  • Symptoms of a clinically relevant illness in the 3 weeks before the first study day

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Clinical Pharmacology, Medical University of Vienna

Vienna, Vienna, 1090, Austria

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, assco. Prof.

Study Record Dates

First Submitted

June 18, 2012

First Posted

June 20, 2012

Study Start

June 1, 2012

Primary Completion

June 1, 2012

Study Completion

June 1, 2012

Last Updated

July 2, 2012

Record last verified: 2012-06

Locations