The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars
1 other identifier
interventional
6
1 country
1
Brief Summary
While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our assessing the effects of fractional vascular lasers on burn scars. It has been hypothesized that the fractional vascular lasers work on mature scars to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. The retexturing/ resurfacing of the laser theoretically can decrease the visibility of the mesh pattern created by meshed split thickness skin graft). Objective: To determine the benefit of fractional vascular laser treatment in improving burn scar height, texture, vascularity and pliability in late burn scars.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Nov 2012
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 12, 2012
CompletedFirst Posted
Study publicly available on registry
June 14, 2012
CompletedStudy Start
First participant enrolled
November 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 1, 2028
December 4, 2024
December 1, 2024
14.6 years
June 12, 2012
December 3, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
reduction in scar appearance
examine with modified Vancouver Scar Scale
every 3 weeks to 15 weeks
Study Arms (2)
Proximal
ACTIVE COMPARATORlocation of the scar proximal to heart
Distal
EXPERIMENTALlocation of scar distal to heart
Interventions
laser energy will be applied to one of 2 sites (proximal or distal) depending on randomization result
Eligibility Criteria
You may qualify if:
- living in Winnipeg
- burn scar 6-12 months old
- Fitzpatrick skin type I-III
- thermal burn scar on trunk or extremities
You may not qualify if:
- open wound
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Manitoba
Winnipeg, Manitoba, R3A 1R9, Canada
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
S Logsetty, MD
University of Manitoba
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
June 12, 2012
First Posted
June 14, 2012
Study Start
November 1, 2012
Primary Completion (Estimated)
June 1, 2027
Study Completion (Estimated)
July 1, 2028
Last Updated
December 4, 2024
Record last verified: 2024-12