NCT01619488

Brief Summary

This study is to determine if the Lap-band system is safe and effective for use in morbidly obese adolescents.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
57

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 23, 2007

Completed
5.1 years until next milestone

First Submitted

Initial submission to the registry

June 7, 2012

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 14, 2012

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 4, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 4, 2016

Completed
7.2 years until next milestone

Results Posted

Study results publicly available

June 8, 2023

Completed
Last Updated

August 1, 2023

Status Verified

July 1, 2023

Enrollment Period

9 years

First QC Date

June 7, 2012

Results QC Date

March 31, 2023

Last Update Submit

July 27, 2023

Conditions

Keywords

Lap-Bandmorbid obesityadolescents

Outcome Measures

Primary Outcomes (1)

  • Total Weight Loss

    Weight loss in kilograms Weight on day of surgery minus last weight recorded before end of trial

    Up to five years post surgery.

Secondary Outcomes (1)

  • Insulin Resistance

    Baseline

Study Arms (1)

Gastric Banding

EXPERIMENTAL

Surgical placement of an adjustable gastric band around the upper portion of the stomach. Adjustments are made to the band through a subcutaneous port as needed to maintain appropriate restriction.

Device: Adjustable Gastric Band

Interventions

Surgical placement of an adjustable gastric band around the upper portion of the stomach. Adjustments are made to the band through a subcutaneous port as needed to maintain appropriate restriction.

Also known as: Lap-Band
Gastric Banding

Eligibility Criteria

Age14 Years - 19 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • ages 14-19
  • BMI \> 35
  • history of obesity for at least 5 years with failed attempts at diet and medical management for at least 6 months.
  • confirmation by a pediatric psychologist that the subject is sufficiently mature emotionally and has adequate family support to comply with the study protocol.

You may not qualify if:

  • history of congenital or acquired anomalies of the GI tract.
  • history of esophageal motility disorders
  • uncontrolled psychiatric problems
  • previous esophageal, gastric or bariatric surgery; intestinal obstruction or peritonitis.
  • uncontrolled eating disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

A I duPont Hospital for Children/Nemours Children's Clinic

Wilmington, Delaware, 19803, United States

Location

MeSH Terms

Conditions

Obesity, Morbid

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Kirk W Reichard, MD, MBA, Surgical Director
Organization
Nemours Childrens Health Delaware

Study Officials

  • Kirk Reichard, MD

    A I duPont Hospital for Children; Nemours Children's Clinic

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
OR SURGICAL DIRECTOR

Study Record Dates

First Submitted

June 7, 2012

First Posted

June 14, 2012

Study Start

April 23, 2007

Primary Completion

April 4, 2016

Study Completion

April 4, 2016

Last Updated

August 1, 2023

Results First Posted

June 8, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations