NCT01616537

Brief Summary

Background Patient satisfaction with or acceptance of care assessment is increasingly taken into account in oncology. Most cancer and other critically-ill patients require a totally-implanted Central Venous Catheter (CVC) for their treatment consisting of a reservoir connected to a central venous catheter, which may or may not be valved. It is impossible to estimate the number of CVC used in oncology. However, some authors claim that, in 2005, over 7 million CVCs were placed in the United States in both chronic and acute care. Although many patients fitted with a CVC are able to undertake activities which are hindered with other external vascular access devices, they are often physically or psychologically anxious about their device. To our knowledge, no validated questionnaire measuring patient acceptance of and satisfaction with their CVC has been reported in the literature. Based on these observations, the aim of our study was to develop and to validate a French-language questionnaire dubbed QASICC (Questionnaire for Acceptance of and Satisfaction with Implanted Central Venous Catheter) assessing patient satisfaction with and acceptance of their CVC. QASICC is designed as a multi-dimensional, self-administered questionnaire comprising approximately 30 items related to the use, appearance and pros and cons of the device as well as quality of life as perceived by patients using one for treatment. Objective The purpose of the study is to validate a French-language self-administered questionnaire (QASICC) designed to evaluate patients' satisfaction and acceptance concerning their totally-implanted central venous catheter: confirmatory validation of questionnaire psychometric properties. Study Design This is a prospective, multicenter, open study. Primary Outcome Measures: Questionnaire's 27 items tested on 990 patients to confirm QASICC internal structure:

  • Items quality
  • Dimensional structure
  • Dimensional consistence
  • Measure accuracy
  • Measure reliability
  • Sensitivity to change

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
990

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2011

Typical duration for not_applicable

Geographic Reach
1 country

10 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

June 7, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 11, 2012

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
Last Updated

November 16, 2015

Status Verified

February 1, 2013

Enrollment Period

2 years

First QC Date

June 7, 2012

Last Update Submit

November 13, 2015

Conditions

Keywords

solid tumorshematological malignancy

Outcome Measures

Primary Outcomes (1)

  • QASICC questionnaire's 27 items tested on 990 patients to confirm the internal structure

    * Items quality * Dimensional structure * Dimensional consistence * Measure accuracy * Measure reliability * Sensitivity to change

    30 days (+/- 7 days) after CVC implantation

Secondary Outcomes (1)

  • Questionnaire's 27 items tested on 990 patients to confirm QASICC external structure: convergent-divergent validity compared to EORTC-QLQC30 questionnaire.

    30 days (+/-7 days) after CVC implantation

Interventions

QASICC AND EORTC QLQ-C30 ADMINISTRATION 30 DAYS AFTER CVC IMPLANTATION

Also known as: QASICC, EORTC QLQ-C30

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years and older
  • Patient who benefited or will benefit from the implantation of a CVC
  • Solid tumor or hematologic malignancy
  • WHO Performance Status 0-2

You may not qualify if:

  • Any severe psychopathological disorder preventing completion of the questionnaire or invalidating questionnaire's measures
  • Severe depressive state
  • Non malignant pathology
  • Inability to respond to questionnaires
  • Patient not speaking fluent French
  • Patient unable to consent
  • Patient under guardianship

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Centre Paul Papin - Ico

Angers, 49933, France

Location

Centre Francois Baclesse

Caen, 14076, France

Location

Chu La Timone

Marseille, 13000, France

Location

Chu de Montpellier

Montpellier, 34295, France

Location

Centre Antoine Lacassagne

Nice, 06189, France

Location

Institut Jean Godinot

Reims, 51056, France

Location

Centre Rene Huguenin

Saint-Cloud, 92210, France

Location

Centre Paul Strauss

Strasbourg, 67065, France

Location

Institut Claudius Regaud

Toulouse, 31052, France

Location

Centre Alexis Vautrin

Vandœuvre-lès-Nancy, 54511, France

Location

MeSH Terms

Conditions

Mast-Cell SarcomaHematologic Neoplasms

Condition Hierarchy (Ancestors)

MastocytosisNeoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsMast Cell Activation DisordersImmune System DiseasesNeoplasms by SiteHematologic DiseasesHemic and Lymphatic Diseases

Study Officials

  • PIERRE YVES MARCY, MD

    Centre Antoine Lacassagne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 7, 2012

First Posted

June 11, 2012

Study Start

November 1, 2011

Primary Completion

November 1, 2013

Study Completion

December 1, 2013

Last Updated

November 16, 2015

Record last verified: 2013-02

Locations