NCT01615588

Brief Summary

Five high methylglyoxal (460-667 mg/kg) Manuka honey samples were selected from different geographical locales around the North Island of New Zealand and tested for glycaemic index (GI) in 10 healthy volunteers in a single-blinded, randomised study. Participants were fed honey containing 25g of available carbohydrate in 200 ml water and the blood glucose responses measured (area under the curve; AUC) and compared to that of 25 g of available carbohydrate from glucose.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable healthy

Timeline
Completed

Started Apr 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2012

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2012

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

June 6, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 8, 2012

Completed
Last Updated

June 8, 2012

Status Verified

June 1, 2012

Enrollment Period

Same day

First QC Date

June 6, 2012

Last Update Submit

June 7, 2012

Conditions

Healthy

Keywords

manuka honeyglycaemic indexblood glucose controlindividualscurrent diseasemedication use

Outcome Measures

Primary Outcomes (1)

  • Determine the Glycaemic index of Manuka honey

    10 healthy individuals consumed honey (25g of available carbohydrate in 200 ml of water) in a fasted state. Blood glucose levels were recorded at 0, 15, 30, 45, 60, 90 and 120 mins and the area under the blood glucose curve was calculated. All 10 participants took five different honeys and a glucose standard on six different days (with randomised allocation of samples).

    2 weeks

Study Arms (1)

honey

EXPERIMENTAL

Manuka honey

Dietary Supplement: Manuka Honey

Interventions

Manuka HoneyDIETARY_SUPPLEMENT

honey was weighed out to provide 25 g of available carbohydrate in 200 ml of water

Also known as: Manuka Health New Zealand Manuka honey
honey

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy (Body mass index (BMI) 20-25)
  • non-smoking
  • aged between 18-45 years
  • absence of diabetes or chronic illness
  • not taking any medications.

You may not qualify if:

  • currently dieting
  • suffering from illness or chronic disease
  • currently taking medication
  • smokers (including recreational)
  • outside healthy BMI range

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Waiariki Institute of Technology

Rotorua, BOP, 3046, New Zealand

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Lecturer

Study Record Dates

First Submitted

June 6, 2012

First Posted

June 8, 2012

Study Start

April 1, 2012

Primary Completion

April 1, 2012

Study Completion

April 1, 2012

Last Updated

June 8, 2012

Record last verified: 2012-06

Locations

NZ(1)