Physical Activity, Sleep and Age

NCT01609764 | Completed

• 1 other identifier: NL40040.068.12
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

Ageing is associated with a reduction of physical activity, movement efficiency, and quality of sleep. This leads to reduced health and well being in elderly subjects. Exercise training can increase movement efficiency and quality of sleep. Objectives:

1. 1.Laboratory validation test of body acceleration based indexes for movement efficiency and quality of sleep;
2. 2.Cross-sectional analysis to assess relations between these indexes and age;
3. 3.Intervention study to assess the effect of exercise training on daily life movement efficiency and quality of sleep in ageing subjects

Conditions

Aging; Movement Efficiency; Sleep

Outcome Measures

Primary Outcomes (1)

• Changes in movement efficiency

  The primary objective is to identify features of body acceleration to be included in an index to assess daily life movement efficiency. Secondly, the index is related with age to quantify how ageing affects daily life movement efficiency. The third objective is to show the effects of regular physical activity training on this index. The expected improvement of the index would show that exercise delays the age related decrease of movement efficiency.

  At baseline and after 1 year

Secondary Outcomes (1)

• Changes in quality sleep

  At baseline and after 1 year

Study Arms (2)

Exercise

EXPERIMENTAL

Follows the fitness program as described in the intervention

Behavioral: One year fitness training

Control

NO INTERVENTION

Will not follow any regular fitness activity during one year

Interventions

One year fitness training BEHAVIORAL

Regular training schedule of moderate intensity, at 50% of heart rate reserve, as available for the specific age group in fitness centres

Exercise

Eligibility Criteria

• Age: 50 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Men and women
• Age between 50-85 years
• No fitness activity in the previous year, to amplify training effects on movement efficiency and quality of sleep.
• Body mass index between 20 and 30 kg/m2, obesity limits the training capacity of subjects.
• Signed informed consent by the participants

You may not qualify if:

• Age below 50 or above 85 years;
• body mass index below 20 kg/m2 or above 30 kg/m2;
• neurologic, cardiologic or invalidating orthopaedic disease;
• pregnancy or lactation.

Sponsors & Collaborators

• Maastricht University Medical Center: lead

Study Sites (1)

Maastricht University

Maastricht, Limburg, 6200 MD, Netherlands

Location

Related Publications (1)

• Valenti G, Bonomi AG, Westerterp KR. Walking as a Contributor to Physical Activity in Healthy Older Adults: 2 Week Longitudinal Study Using Accelerometry and the Doubly Labeled Water Method. JMIR Mhealth Uhealth. 2016 Jun 7;4(2):e56. doi: 10.2196/mhealth.5445.

  PMID: 27268471 DERIVED

Study Officials

• Klaas R Westerterp, Professor

  Maastricht University, NUTRIM, Human biology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 18, 2012
• First Posted: June 1, 2012
• Study Start: January 1, 2013
• Primary Completion: October 1, 2013
• Study Completion: October 1, 2014
• Last Updated: March 16, 2016

Record last verified: 2015-04

Locations

NL (1)