NCT01603992

Brief Summary

Background: \- Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment ( spontaneous quitting). Studies have suggested that there are some common strategies that many individuals use in spontaneous quitting, such as changing one s lifestyle or identity, reminding oneself of negative consequences, support from family and friends, and religion. However, more research is needed to determine potential treatment strategies for marijuana use. Objectives:

  • To identify strategies used to help with marijuana quitting among non-treatment seeking adult marijuana users.
  • To identify withdrawal symptoms experienced during marijuana quitting and their relationship to the quitting strategies used and the outcome of the quit attempt.
  • To evaluate whether subgroups of marijuana users differ in their experience of marijuana quitting. Eligibility: \- Individuals at least 18 years of age who have made at least one attempt to quit marijuana use. Design:
  • The study will consist of one visit of approximately 1 to 2 hours.
  • Participants will fill out three questionnaires. The questionnaires have different types of questions, and will ask about background and lifestyle, marijuana use and craving patterns and behaviors, and difficulties in previous attempts to quit using marijuana.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
822

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2005

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 8, 2005

Completed
6.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 3, 2012

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

May 19, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 23, 2012

Completed
Last Updated

April 5, 2018

Status Verified

May 3, 2012

First QC Date

May 19, 2012

Last Update Submit

April 4, 2018

Conditions

Cannabis AbuseCannabis Dependence

Keywords

CannabisCravingQuestionnaireNon-TreatmentDrug Use

Outcome Measures

Primary Outcomes (1)

  • Marijuana Quit Questionnaire

    1 to 2 hours

Secondary Outcomes (1)

  • Marijuana Craving Questionnaire, and Additional Questions about Marijuana Craving

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age 18 or older
  • have made at least one attempt to quit marijuana use
  • able to give valid informed consent
  • ability to understand English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

National Institute on Drug Abuse, Biomedical Research Center (BRC)

Baltimore, Maryland, 21224, United States

Location

Maryland Psychiatric Research Center (MPRC) 55 Wade Avenue

Catonsville, Maryland, 21228, United States

Location

Medical University of S. Carolina

Charleston, South Carolina, 29425, United States

Location

Related Publications (5)

  • Adamson SJ, Sellman JD. A prototype screening instrument for cannabis use disorder: the Cannabis Use Disorders Identification Test (CUDIT) in an alcohol-dependent clinical sample. Drug Alcohol Rev. 2003 Sep;22(3):309-15. doi: 10.1080/0959523031000154454.

    PMID: 15385225BACKGROUND

  • Boyd SJ, Tashkin DP, Huestis MA, Heishman SJ, Dermand JC, Simmons MS, Gorelick DA. Strategies for quitting among non-treatment-seeking marijuana smokers. Am J Addict. 2005 Jan-Feb;14(1):35-42. doi: 10.1080/10550490590899835.

    PMID: 15804875BACKGROUND

  • Budney AJ, Hughes JR, Moore BA, Vandrey R. Review of the validity and significance of cannabis withdrawal syndrome. Am J Psychiatry. 2004 Nov;161(11):1967-77. doi: 10.1176/appi.ajp.161.11.1967.

    PMID: 15514394BACKGROUND

  • Koola MM, Boggs DL, Kelly DL, Liu F, Linthicum JA, Turner HE, McMahon RP, Gorelick DA. Relief of cannabis withdrawal symptoms and cannabis quitting strategies in people with schizophrenia. Psychiatry Res. 2013 Oct 30;209(3):273-8. doi: 10.1016/j.psychres.2013.07.044. Epub 2013 Aug 20.

    PMID: 23969281DERIVED

  • Boggs DL, Kelly DL, Liu F, Linthicum JA, Turner H, Schroeder JR, McMahon RP, Gorelick DA. Cannabis withdrawal in chronic cannabis users with schizophrenia. J Psychiatr Res. 2013 Feb;47(2):240-5. doi: 10.1016/j.jpsychires.2012.10.010. Epub 2012 Nov 10.

    PMID: 23146560DERIVED

MeSH Terms

Conditions

Marijuana Abuse

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Study Officials

  • David A Gorelick, M.D.

    National Institute on Drug Abuse (NIDA)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 19, 2012

First Posted

May 23, 2012

Study Start

November 8, 2005

Study Completion

May 3, 2012

Last Updated

April 5, 2018

Record last verified: 2012-05-03

Locations

US(3)