Yoga And Cardiovascular Health Trial
YACHT
1 other identifier
interventional
80
1 country
1
Brief Summary
The benefits of alternative therapeutic approaches, such as yoga, are poorly understood and this is particularly true of the beneficial effects on cardiovascular disease (CVD) risk. It is hoped that a better understanding of the value of this therapy will provide a sound scientific basis for including yoga in mainstream clinical practice. The investigators propose to study a group of 80 participants (40 Indian Asians and 40 Europeans) recruited from a cardiac rehabilitation programme in West London post-angioplasty as treatment for an acute coronary syndrome. Those who agree will undergo a series of baseline and follow-up measurements. 20 Indian Asians and 20 Europeans will be randomized to the yoga intervention plus their standard cardiac rehabilitation programme (usual care), and the remaining 20 Indian Asians and 20 Europeans will be randomized to usual care alone. Baseline and follow-up measurements will be performed on all participants. In order to determine the acute effects of yoga the group randomised to the yoga intervention will also undergo a series of acute tests before and after their first yoga session.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jun 2012
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 8, 2012
CompletedFirst Posted
Study publicly available on registry
May 15, 2012
CompletedStudy Start
First participant enrolled
June 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2013
CompletedNovember 11, 2016
June 1, 2012
10 months
May 8, 2012
November 10, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Cardiopulmonary function
To perform a mechanistic study that determines the acute and chronic effects of yoga on cardiopulmonary function, autonomic function, blood pressure and heart rate.
Week 0 (pre intervention) and week 12 (post intervention)
Secondary Outcomes (6)
Blood pressure
Week 0 (pre intervention), week 1 (pre & post 1st yoga class), and week 12 (post intervention)
Heart rate and heart rate variability
Week 0 (pre intervention), week 1 (pre & post 1st yoga class), and week 12 (post intervention)
Stress hormones
Week 0 (pre intervention), week 1 (pre & post 1st yoga class), and week 12 (post intervention)
Exercise capacity
Week 0 (pre intervention), week 1 (pre & post 1st yoga class), and week 12 (post intervention)
Body fat
Week 0 (pre intervention) and week 12 (post intervention)
- +1 more secondary outcomes
Study Arms (2)
Yoga 12 week programme
ACTIVE COMPARATORUsual care (standard cardiac rehabilitation programme) plus yoga intervention.
Usual care
NO INTERVENTIONUsual care (standard cardiac rehabilitation programme) only.
Interventions
Those randomised to usual care plus the yoga intervention will be required to attend yoga classes twice a week for 12 weeks alongside their cardiac rehabilitation programme. There will be 24 yoga classes in total, of which, we require the participant to attend a minimum of 18. The yoga classes will be conducted by a teacher certified in yoga and cardiac rehabilitation and will encompass physical fitness (yoga poses), stress reduction (breath control and meditation) and positive lifestyle changes (diet, smoking and alcohol).
Eligibility Criteria
You may qualify if:
- Aged 35-80 years.
- Male or female.
- European or Indian Asian descent.
- Able to understand English or Punjabi.
- Referred to a cardiac rehabilitation programme in West London post-angioplasty as treatment for an acute coronary syndrome.
You may not qualify if:
- Adults under 35 years or above 80 years.
- Adults aged 35-80 years who are not competent to give consent.
- Co-morbid disease or mobility limitations that would preclude participation in cardiac rehabilitation and our investigations.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
International Centre for Circulatory Health
London, W2 1LA, United Kingdom
Related Publications (1)
Tillin T, Tuson C, Sowa B, Chattopadhyay K, Sattar N, Welsh P, Roberts I, Ebrahim S, Kinra S, Hughes A, Chaturvedi N. Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. BMJ Open. 2019 Nov 3;9(11):e030119. doi: 10.1136/bmjopen-2019-030119.
PMID: 31685500DERIVED
MeSH Terms
Conditions
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Nishi Chaturvedi
Imperial College London
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 8, 2012
First Posted
May 15, 2012
Study Start
June 1, 2012
Primary Completion
April 1, 2013
Study Completion
April 1, 2013
Last Updated
November 11, 2016
Record last verified: 2012-06