NCT01590420

Brief Summary

The purpose of this study is to estimate the cost-utility of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients in Sao Paulo city, Brazil, after 3 years of treatment and to estimate the cost-effectiveness of CPAP on the number of medical visits, hospitalizations, medical examinations, used medications, new case incidence and cost of traffic accidents and absence from work. It is also designed to estimate quality-adjusted extended years of life, and to assess cost-effects of the therapy (device, masks, supplies, maintenance/year for membership of professional consulting, electric power) on the cost-effectiveness

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Mar 2011

Typical duration for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2011

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

May 1, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 3, 2012

Completed
1.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2014

Completed
Last Updated

May 3, 2012

Status Verified

May 1, 2012

Enrollment Period

Same day

First QC Date

May 1, 2012

Last Update Submit

May 2, 2012

Conditions

Keywords

OSASleepCPAPCost

Outcome Measures

Primary Outcomes (3)

  • costs of medical events post CPAP treatment

    To evaluate the health satuts costs post-CPAP treatment.

    3 years

  • Number of hospitalizations

    3 years

  • Changes in medications

    3 years

Secondary Outcomes (1)

  • Costs relative to CPAP treatment

    3 years

Study Arms (1)

CPAP treatment

EXPERIMENTAL

1000 patients with 3-years CPAP treatment after a PSG titration

Device: CPAP S8- Scape / Resmed

Interventions

The pressure for treatment is according to PSG titration

Also known as: S8 Escape, Resmed
CPAP treatment

Eligibility Criteria

Age30 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Both genders
  • Aged 30 to 70 years old
  • AHI \> 30 events/hour

You may not qualify if:

  • Patients residing in other cities and states other than São Paulo / SP / Brazil
  • Patients with no fixed residence
  • Previous CPAP contact

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Associação Fundo de Incentivo à Pesquisa

São Paulo, São Paulo, 04024-002, Brazil

RECRUITING

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Camila F Rizzi, PhD

    Federal University of São Paulo

    PRINCIPAL INVESTIGATOR
  • Dalva Poyares, PhD

    Federal University of São Paulo

    STUDY CHAIR
  • Sergio Tufik, PhD

    Federal University of São Paulo

    STUDY DIRECTOR
  • Marcos F Bosi, PhD

    Federal University of São Paulo

    STUDY CHAIR

Central Study Contacts

Dalva Poyares, PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD

Study Record Dates

First Submitted

May 1, 2012

First Posted

May 3, 2012

Study Start

March 1, 2011

Primary Completion

March 1, 2011

Study Completion

March 1, 2014

Last Updated

May 3, 2012

Record last verified: 2012-05

Locations