NCT01589042

Brief Summary

To collect data from real-world use with the Chocolate PTA Balloon Catheter to support the effectiveness of the device for use during percutaneous transluminal angioplasty (PTA) procedures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
490

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2012

Typical duration for all trials

Geographic Reach
1 country

13 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 27, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 1, 2012

Completed
Same day until next milestone

Study Start

First participant enrolled

May 1, 2012

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

September 11, 2018

Status Verified

September 1, 2018

Enrollment Period

3.6 years

First QC Date

April 27, 2012

Last Update Submit

September 7, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Achievement of Optimal PTA

    Percentage of PTA cases in which \<30% diameter stenosis without a flow limiting dissection is achieved without the need for bail-out stenting

    average of 2 hours

Study Arms (2)

Above the Knee

Patients treated with the Chocolate balloon for a lesion located above the knee

Below the Knee

Patients treated with the Chocolate balloon for a lesion located below the knee

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with Peripheral Arterial Disease appropriate for treatment with balloon angioplasty

You may qualify if:

  • \>18 years of age
  • Lesion successfully crossed with a guide-wire
  • Reference Vessel Diameter (RVD) within the treatment range of the Chocolate PTA Catheter used at the target lesion appropriate for 1:1 dilatation
  • Patient has given consent for their information to be submitted to this registry

You may not qualify if:

  • Lesion required stenting as the primary treatment approach
  • Life expectancy \<12 months
  • Patient is enrolled in another clinical study that may impact the results of this registry

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (13)

Arizona Heart Institute

Phoenix, Arizona, United States

Location

Desert Cardiology

Rancho Mirage, California, United States

Location

Cardiovascular Research of North Florida

Gainesville, Florida, United States

Location

Mount Sinai Medical Center

Miami, Florida, United States

Location

Alexian Brothers Heart and Vascular

Elk Grove Village, Illinois, United States

Location

St. Elizabeth's Medical Center

Boston, Massachusetts, 02135, United States

Location

St. John's Hospital

Detroit, Michigan, United States

Location

Metro Health Hospital

Wyoming, Michigan, 49519, United States

Location

Jackson Heart Clinic

Jackson, Mississippi, United States

Location

Rex Health

Raleigh, North Carolina, United States

Location

Cardiovascular Research of Dallas

Dallas, Texas, United States

Location

VA North Texas

Dallas, Texas, United States

Location

Wheaton Franciscan Healthcare

Racine, Wisconsin, United States

Location

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular Diseases

Study Officials

  • Jihad Mustapha, MD

    Metro Health Hospital

    PRINCIPAL INVESTIGATOR
  • Lawrence Garcia, MD

    St Elizabeth's Med Center / Tufts Univ School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 27, 2012

First Posted

May 1, 2012

Study Start

May 1, 2012

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

September 11, 2018

Record last verified: 2018-09

Locations