Group Balance Training for People With Multiple Sclerosis

NCT01582126 | Completed

• 1 other identifier: Ö-1-12
• Study Type: interventional
• Target: 87
• Locations: 1 country
• Sites: 7

Brief Summary

People with multiple sclerosis (MS) often have affected balance capacity and an increased risk for falls. A risk factor for falls are activities requiring dual attention. Another factor leading to reduced balance capacity is trunk stability, and decreased trunk stability has been seen in people with MS compared to healthy controls. Earlier studies using core stability exercises have shown positive effects on balance, compared to no training. In Sweden, physical therapy for people with MS has often included group training. However, evidence for this intervention is scarce. The aim of this study is therefore to investigate balance training in group. The balance training includes core stability exercises and dual attention activities. A multi-centre study is planned with a waiting-list design. Participants are randomised to either exercise group with early start or with late start. The group balance training includes training 60 minutes 2 times per week for 7 weeks.

Conditions

Multiple Sclerosis

Keywords

multiple sclerosis; physical therapy; postural control

Outcome Measures

Primary Outcomes (1)

• Change from Baseline in Bergs balance scale

  Functional balance scale in sitting, standing and walking.

  Change from Baseline in Bergs balance scale at 7 weeks

Secondary Outcomes (15)

• Change from Baseline in Four Square step test

  Change from Baseline in Four Square step test at 7 weeks

• Change from baseline in Timed chair stands test

  Change from baseline in Times Chair stands test at 7 weeks

• Change from baseline in Timed Up and Go test

  Change from baseline in Timed Up and Go test at 7 weeks

• Change from baseline in Functional Gait Assessment

  Change from baseline in Functional Gait Assessment at 7 weeks

• Change from baseline in Postural sway

  Change from baseline in Postural sway at 7 weeks

Study Arms (2)

Group balance training early start

EXPERIMENTAL

Other: Group balance training

Group balance training late start

EXPERIMENTAL

Other: Group balance training

Interventions

Group balance training OTHER

Balance training i group with focus on core stability exercises and dual attention activities.

Group balance training early start; Group balance training late start

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed multiple sclerosis by a neurologist, being able to walk 100 m with or without walking device, being able to get down on the floor with minor assistance

You may not qualify if:

• No balance deficit here defined as being able to stand still heel-toe for 30 seconds with arms crossed.
• Ongoing relapse, cognitive- or language difficulties that prohibits performing the outcome measures.

Sponsors & Collaborators

• Örebro County Council: lead
• Uppsala-Örebro Regional Research Council: collaborator
• Norrbacka-Eugenia Foundation: collaborator

Study Sites (7)

Mälarsjukhuset

Eskilstuna, 63188, Sweden

Location

Karlstad hospital

Karlstad, Sweden

Location

Rörelse och hälsa neuro

Linköping, Sweden

Location

Primärvård Mjölby

Mjölby, Sweden

Location

Nyköpings hospital

Nyköping, Sweden

Location

University Hospital Örebro

Örebro, 70185, Sweden

Location

Västerås hospital

Västerås, 72189, Sweden

Location

Related Publications (1)

• Nilsagard YE, von Koch LK, Nilsson M, Forsberg AS. Balance exercise program reduced falls in people with multiple sclerosis: a single-group, pretest-posttest trial. Arch Phys Med Rehabil. 2014 Dec;95(12):2428-34. doi: 10.1016/j.apmr.2014.06.016. Epub 2014 Jul 6.

  PMID: 25004466 DERIVED

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Anette Forsberg, PhD

  Family Medicine Research Centre, Örebro county council

  STUDY CHAIR

• Ylva Nilsagård, PhD

  Centre for Health Care Sciences, Örebro county council

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Researcher, RPT

Study Record Dates

• First Submitted: April 16, 2012
• First Posted: April 20, 2012
• Study Start: August 1, 2012
• Primary Completion: July 1, 2013
• Study Completion: July 1, 2013
• Last Updated: March 27, 2015

Record last verified: 2015-03

Locations

SE (7)