NCT01574001

Brief Summary

The primary objective of the present randomized controlled trial is to compare the effectiveness of three anti-smoking interventions of different intensities. It has been hypothesised that early follow-up visits facilitate post-stroke smoking cessation in patients hospitalized because of first-ever ischemic stroke.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
240

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 1, 2012

Completed
Same day until next milestone

Study Start

First participant enrolled

April 1, 2012

Completed
9 days until next milestone

First Posted

Study publicly available on registry

April 10, 2012

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

May 15, 2013

Status Verified

April 1, 2012

Enrollment Period

1.7 years

First QC Date

April 1, 2012

Last Update Submit

May 14, 2013

Conditions

Keywords

ischemic strokesmoking cessationantismoking interventions

Outcome Measures

Primary Outcomes (1)

  • Smoking cessation rate

    12 months

Study Arms (3)

Antismoking intervention with minimal early follow-up

EXPERIMENTAL

an intervention according to the "5A's" model with one follow-up visit within one week after discharge from the hospital; follow-up assessment will include two visits: 3 and 12 months after stroke

Behavioral: Antismoking intervention with minimal early follow-up

Antismoking intervention with no early follow-up

ACTIVE COMPARATOR

an anti-smoking intervention in line with the "5A's" method without early follow-up; follow-up assessment will be limited to two visits: 3 and 12 months after stroke

Behavioral: Antismoking intervention with no early follow-up

Antismoking intervention with intensive early follow-up

EXPERIMENTAL

an anti-smoking intervention in line with the "5A's" method will be given, including four follow-up visits within 6 weeks after discharge from the hospital (week 1, week 2, week 4, week 6 after stroke); follow-up assessment will include two visits: 3 and 12 months after stroke

Behavioral: Antismoking intervention with intensive early follow-up

Interventions

an anti-smoking intervention in line with the "5A's" method without early follow-up; follow-up assessment will be limited to two visits: 3 and 12 months after stroke

Antismoking intervention with no early follow-up

Anti-smoking intervention in line with the "5A's" method (Ask, Advice, Assess, Assist, Arrange follow-up. The intervention will be carried out 5-7 days after stroke, before the planned discharge from the hospital. Seven days after discharge from a stroke unit a brief telephone/personal advice will be given aimed to motivate patients to quit smoking; follow-up assessment will include two visits: 3 and 12 months after stroke

Antismoking intervention with minimal early follow-up

an anti-smoking intervention in line with the "5A's" method will be given, including four follow-up visits within 6 weeks after discharge from the hospital (week 1, week 2, week 4, week 6 after stroke); follow-up assessment will include two visits: 3 and 12 months after stroke

Antismoking intervention with intensive early follow-up

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients smoking immediately prior to stroke
  • The first in the lifetime ischemic stroke
  • Ability to understand the research protocol procedures and cooperation during the investigation
  • Reported availability of and declaration to participate in follow-up
  • Informed consent to participate in the study

You may not qualify if:

  • Severe stroke
  • Stroke onset more than 3 weeks before admission
  • History of previous stroke with clinical symptoms
  • Hemorrhagic stroke
  • Diagnosis of dementia or presence of other neurological disease (Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's chorea, a previous subarachnoid haemorrhage, meningitis, cerebral trauma in an interview)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Psychiatry and Neurology

Warsaw, 02-957, Poland

RECRUITING

MeSH Terms

Conditions

Ischemic StrokeSmoking Cessation

Condition Hierarchy (Ancestors)

StrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesHealth BehaviorBehavior

Study Officials

  • Halina Sienkiewicz-Jarosz, M.D., PhD

    1st Department of Neurology, Institute of Psychiatry and Neurology, 9 Sobieskiego Str., 02-957 Warsaw, Poland

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Halina Sienkiewicz-Jarosz, M.D., PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 1, 2012

First Posted

April 10, 2012

Study Start

April 1, 2012

Primary Completion

December 1, 2013

Study Completion

December 1, 2014

Last Updated

May 15, 2013

Record last verified: 2012-04

Locations