NCT01573195

Brief Summary

The purpose of this study is to pilot the use of best practices alerts to enhance an antimicrobial stewardship program using the electronic medical record, EPIC.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,285

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2011

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 4, 2011

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2012

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 6, 2012

Completed
Last Updated

December 18, 2014

Status Verified

December 1, 2014

Enrollment Period

1.1 years

First QC Date

May 4, 2011

Last Update Submit

December 16, 2014

Conditions

Antibiotic Resistant Infection

Keywords

deescalationbest practice alertantimicrobial stewardship

Outcome Measures

Primary Outcomes (1)

  • Percentage of best practice alerts(BPA) that were completely accepted, partially accepted, or rejected within 72 hours of issuing the BPA

    after issuing the BPA for deescalation, the responding healthcare provider will respond in one of the manners above

    One Year

Secondary Outcomes (1)

  • The number and type of antiinfectives that were administered before and after(11days) the best practice alert is issued.

    One year

Study Arms (1)

All prescribing MDs at UWHC

Observational for accept, reject, or accept with modification of Best Practice Alers

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

1285 consecutive patients issued BPA for de-escalation of antibiotics in EPIC

You may qualify if:

  • Physicians with prescribing privileges at the UWHC

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin Hospitals and Clinics

Madison, Wisconsin, 53792, United States

Location

Related Publications (1)

  • Schulz L, Osterby K, Fox B. The use of best practice alerts with the development of an antimicrobial stewardship navigator to promote antibiotic de-escalation in the electronic medical record. Infect Control Hosp Epidemiol. 2013 Dec;34(12):1259-65. doi: 10.1086/673977. Epub 2013 Oct 28.

    PMID: 24225610RESULT

Study Officials

  • Barry C Fox, MD

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 4, 2011

First Posted

April 6, 2012

Study Start

March 1, 2011

Primary Completion

April 1, 2012

Study Completion

April 1, 2012

Last Updated

December 18, 2014

Record last verified: 2014-12

Locations

US(1)