NCT01566955

Brief Summary

The main reason for this trial is to show the feasibility of removing the ovarien and fallopian tubes through the gaster (transgastric adnexectomy). The background for it is to look for more indications of scarless surgery and we will show that the transgastric adnexectomy can be performed in an easy way. It is necessary that there is an indication for removing the ovaries and fallopian tubes and if the patient agree we will do it instead of through the belly through the gaster and maybe with an additional inzision in the vagina. All patients with indication for adnexectomy are potential candidates.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 22, 2012

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 30, 2012

Completed
2 days until next milestone

Study Start

First participant enrolled

April 1, 2012

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

May 27, 2015

Status Verified

May 1, 2015

Enrollment Period

2.7 years

First QC Date

March 22, 2012

Last Update Submit

May 26, 2015

Conditions

Keywords

transgastricNOTESGastrotomyBRCA 1/2

Outcome Measures

Primary Outcomes (1)

  • Number of Participants with conversion to laparoscopy or laparotomy

    With the trial we want to demonstrate that the transgastric adnexectomy is possible. We will document the number of patients in which we have to change the transgastric to a laparoscopic or laparotomic operation.

    12 months

Secondary Outcomes (1)

  • postoperative well being

    6 weeks and 6 months

Study Arms (1)

transgastric adnexectomy

EXPERIMENTAL

patients are operated transgastric

Procedure: transgastric adnexectomy

Interventions

adnexectomy transgastrically with transvaginal support

Also known as: NOTES, Pure NOTES
transgastric adnexectomy

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Indication for adnexectomy, agreement to take part in the study

You may not qualify if:

  • No agreement in the trial; patients younger than 18 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Medical Center Mannheim

Mannheim, Baden-Wurttemberg, 68135, Germany

Location

Related Publications (1)

  • Hornemann A, Suetterlin M, Trunk MJ, Gerhardt A, Kaehler G. Pure natural orifice transluminal endoscopic surgery (NOTES) involving peroral endoscopic salpingo-oophorectomy (POESY). Int J Gynaecol Obstet. 2014 Apr;125(1):86-8. doi: 10.1016/j.ijgo.2013.08.024. Epub 2014 Jan 2.

    PMID: 24434232BACKGROUND

MeSH Terms

Conditions

Ovarian Diseases

Condition Hierarchy (Ancestors)

Adnexal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital DiseasesGonadal DisordersEndocrine System Diseases

Study Officials

  • Marc Suetterlin, MD; PhD

    University of Heidelberg, University Medical Center Mannheim Department of Obstetric and Gynaecology

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Amadeus Hornemann, MPH, PhD

Study Record Dates

First Submitted

March 22, 2012

First Posted

March 30, 2012

Study Start

April 1, 2012

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

May 27, 2015

Record last verified: 2015-05

Locations