NCT01550952

Brief Summary

Total shoulder arthroplasty (shoulder replacement) can cause severe postoperative pain. Commonly, patients receive general anesthesia with interscalene block (injection of local anesthetic or numbing medicine near nerves in the shoulder) during surgery. As a result of the interscalene block, patients often experience sensory and motor blockade. The purpose of this study is to determine the effects of the interscalene block on the anterior deltoid muscle and hand grip strength after total shoulder arthroplasty.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2011

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2012

Completed
29 days until next milestone

First Submitted

Initial submission to the registry

March 1, 2012

Completed
11 days until next milestone

First Posted

Study publicly available on registry

March 12, 2012

Completed
4.1 years until next milestone

Results Posted

Study results publicly available

March 31, 2016

Completed
Last Updated

March 31, 2016

Status Verified

September 1, 2012

Enrollment Period

2 months

First QC Date

March 1, 2012

Results QC Date

January 29, 2016

Last Update Submit

March 1, 2016

Conditions

Outcome Measures

Primary Outcomes (2)

  • Anterior Deltoid Strength

    Anterior deltoid strength as measured by a dynamometer. Percentage change in measure as compared to post-surgery (with post-surgery measure at 0%).

    2 days postoperatively

  • Hand Grip Strength

    Hand grip strength as measured by a dynamometer. Percentage change in measure as compared to post-surgery (with post-surgery measure at 0%).

    2 days postoperatively

Secondary Outcomes (3)

  • Number of Participants With Reduced Sensation in a Dermatome

    2 days postoperatively

  • Numeric Rating Scale (NRS) Pain Scores With Movement

    2 days postoperatively

  • Total Oral Opioid Intake in 48hrs

    0-48hrs

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients 18-80 years old who are undergoing primary total shoulder arthroplasty.

You may qualify if:

  • Patients scheduled for primary total shoulder arthroplasty
  • Age 18 to 80 years old
  • Planned use of general anesthesia via laryngeal mask airway (LMA) and peripheral nerve block
  • Ability to follow study protocol
  • Patients with American Society of Anesthesiologists (ASA) physical status of I, II or III

You may not qualify if:

  • Patients younger than 18 years old and older than 80
  • Patients not intending to receive general anesthesia and peripheral nerve block
  • Allergy or intolerance to one of the study medications
  • Patients with an ASA of IV
  • Hepatic or renal insufficiency
  • Chronic opioid use (taking opioids for longer than 3 months)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital for Special Surgery

New York, New York, 10021, United States

Location

Results Point of Contact

Title
Dr. Jacques YaDeau
Organization
Hospital for Special Surgery

Study Officials

  • Jacques T YaDeau, MD, PhD

    Hospital for Special Surgery, New York

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 1, 2012

First Posted

March 12, 2012

Study Start

December 1, 2011

Primary Completion

February 1, 2012

Study Completion

February 1, 2012

Last Updated

March 31, 2016

Results First Posted

March 31, 2016

Record last verified: 2012-09

Locations