NCT01545765

Brief Summary

The purpose of this study is to evaluate the duration of anesthetic effect produced , Lidocaine7% + Tetracaine 7% cream when applied with 2 different application times on the face and thigh.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at P50-P75 for phase_4 healthy-volunteers

Timeline
Completed

Started May 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 24, 2012

Completed
12 days until next milestone

First Posted

Study publicly available on registry

March 7, 2012

Completed
2 months until next milestone

Study Start

First participant enrolled

May 1, 2012

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2012

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

September 4, 2013

Completed
Last Updated

September 2, 2021

Status Verified

June 1, 2013

Enrollment Period

Same day

First QC Date

February 24, 2012

Results QC Date

June 25, 2013

Last Update Submit

August 31, 2021

Conditions

Keywords

Healthy volunteers

Outcome Measures

Primary Outcomes (1)

  • Duration of Anesthesia(Minutes)

    Onset and end of anesthesia are evaluated by Pinprick tests. Duration of anesthesia is calculated as: difference between onset and end of anesthesia (minutes).

    From T0 (product removal) up to T8 hours after product removal

Secondary Outcomes (1)

  • Adverse Events

    During the study

Study Arms (1)

lidocaine 7% and tetracaine 7%

EXPERIMENTAL
Drug: Lidocaine 7% + Tetracaine 7% cream

Interventions

Study drug will be applied with a different application time to one side of the face and anterior thigh according to the randomization list.

lidocaine 7% and tetracaine 7%

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy male of female subjects aged 18 or older with a normal not excessive hairy skin,

You may not qualify if:

  • Female subjects who are pregnant or breast-feeding; or plan to become pregnant,
  • Subjects who have a known allergy to one of the components of the test drug lidocaine, tetracaine or other local anesthetics,
  • Subjects who are at risk in terms of precautions, warnings, and contra-indication with the study product.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Galderma Investigational center

Rochelle Park, New Jersey, United States

Location

MeSH Terms

Interventions

LidocaineTetracaine

Intervention Hierarchy (Ancestors)

AcetanilidesAnilidesAmidesOrganic ChemicalsAniline CompoundsAminespara-AminobenzoatesAminobenzoatesBenzoatesAcids, CarbocyclicCarboxylic AcidsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbons

Limitations and Caveats

No limitation or caveat on this study

Results Point of Contact

Title
Farzaneh Sidou Clinical Project Manager)
Organization
Galderma

Study Officials

  • Regina YAVEL, MD- Dermatologist

    Galderma investigational center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 24, 2012

First Posted

March 7, 2012

Study Start

May 1, 2012

Primary Completion

May 1, 2012

Study Completion

May 1, 2012

Last Updated

September 2, 2021

Results First Posted

September 4, 2013

Record last verified: 2013-06

Locations