A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products
1 other identifier
interventional
40
1 country
1
Brief Summary
Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents. This study aims to compare the effect of saline and hydrogen peroxide on the tensile strength of 4-0 nylon sutures following removal from a cutaneous surgical wound.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2010
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2011
CompletedFirst Submitted
Initial submission to the registry
February 10, 2012
CompletedFirst Posted
Study publicly available on registry
February 15, 2012
CompletedMay 10, 2017
May 1, 2017
1.3 years
February 10, 2012
May 9, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Tensile strength of 4-0 nylon sutures
The tensile strength was defined as the force required to break the suture, with breaking strength as the maximum strength that a material can withstand when subjected to an applied load, without taking into consideration the cross sectional area. The strength of the sutures was measured using a tensometer.
14 days
Study Arms (2)
Hydrogen peroxide
EXPERIMENTALSaline
ACTIVE COMPARATORInterventions
Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator
Eligibility Criteria
You may qualify if:
- Subject is willing to comply with the informed consent procedures
- Subject's wound is on the body or scalp
- Subject will be able to come to the clinic for suture removal on day 14
You may not qualify if:
- Subject is less than 18 years of age
- Subject's wound was not closed with 4-0 nylon sutures
- Subject's wound is on the face
- Subject plans to apply other topicals to the area under study
- Subject's suture is removed before or after day 14
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
Related Publications (2)
Snyder CC. On the history of the suture. Plast Reconstr Surg. 1976 Oct;58(4):401-6. doi: 10.1097/00006534-197610000-00001. No abstract available.
PMID: 785506RESULTHochberg J, Meyer KM, Marion MD. Suture choice and other methods of skin closure. Surg Clin North Am. 2009 Jun;89(3):627-41. doi: 10.1016/j.suc.2009.03.001.
PMID: 19465201RESULT
MeSH Terms
Conditions
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, CARE PROVIDER
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Keyvan Nouri, M.D Professor of Dermatology, Ophthalmology & Otolaryngology, Chief of Dermatology Servic
Study Record Dates
First Submitted
February 10, 2012
First Posted
February 15, 2012
Study Start
May 1, 2010
Primary Completion
August 1, 2011
Study Completion
August 1, 2011
Last Updated
May 10, 2017
Record last verified: 2017-05