NCT01532986

Brief Summary

Health care benefits and services are received through the Veterans Health Administration (VHA), a component of the United States Department of Veterans Affairs. Over 40,000 Veterans across the Veterans Health Administration are diagnosed with Parkinson's disease (PD), a chronic condition that affects motor function as well as cognition, mood, sleep, and autonomic function. There are not enough subspecialists to manage every Veteran with Parkinson's disease. However, a care model of nurse care managers as catalysts and advocates using needs assessments, evidence-based protocols, and VHA and community access coordination mechanisms to optimize Parkinson's disease care may improve quality of Parkinson's disease care and patient-centered outcomes. If efficacious, this model may be practical to disseminate via an existing VHA national consortium network for Parkinson's disease. Objectives are (1) to implement then analyze via a randomized controlled trial whether a nurse-led, coordinated care management intervention, Care Coordination for Health Promotion and Activities in Parkinson's Disease (CHAPS), compared to usual care will improve adherence to evidence-based practice guidelines and improve health outcomes in Veterans with Parkinson's disease in a region of the southwest United States, and (2) to analyze extent of implementation of the CHAPS intervention and its costs to determine how the intervention can be made sustainable and disseminated throughout Veterans Affairs Medical Centers if efficacious.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
345

participants targeted

Target at P75+ for not_applicable parkinson-disease

Timeline
Completed

Started Jul 2012

Longer than P75 for not_applicable parkinson-disease

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 13, 2012

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 15, 2012

Completed
5 months until next milestone

Study Start

First participant enrolled

July 9, 2012

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2017

Completed
1.9 years until next milestone

Results Posted

Study results publicly available

March 8, 2019

Completed
Last Updated

March 8, 2019

Status Verified

March 1, 2019

Enrollment Period

4.6 years

First QC Date

January 13, 2012

Results QC Date

March 16, 2018

Last Update Submit

March 7, 2019

Conditions

Keywords

Quality of Health CareNursing Care ManagementCare CoordinationRandomized Trials

Outcome Measures

Primary Outcomes (1)

  • Proportion of Measures Adhered To in the PD Guidelines

    Adherence to quality measures for Parkinson's disease care during study period. We operationalized 18 quality measures: 12 were determined through chart review, and 6 were measured using patient survey data. Range and direction of score: 0 (worst) to 1 (best)

    18 months

Secondary Outcomes (9)

  • Health Utilities Index (HUI3)

    18 months

  • Activities of Daily Living (ADL), (Speech and Swallowing Only)

    18 months

  • Medical Outcomes Study (MOS)

    18 months

  • General Self-Efficacy Scale (GSES)

    18 months

  • Consumer Assessment of Healthcare Providers and Systems (CAHPS)

    18 months

  • +4 more secondary outcomes

Study Arms (2)

Usual Care (Arm 1)

OTHER

Veterans randomized to the usual care arm will continue to receive care they would have received if they had not enrolled in the study; no care or resources that are made available in general by VA will be withheld from participants in either arm or to any Veterans who wish to use those resources. Educational handout: brief educational handout on Parkinson's disease that is available in the VA's "Healthwise for Life" handbook.

Other: Coordinated care management for Parkinson's diseaseOther: Educational handout

Intervention (Arm 2)

EXPERIMENTAL

A delivery system redesign, with nurse care managers, using standardized assessment tools and care coordination protocols to address unmet needs of Veterans with Parkinson's Disease (PD) by collaborating with these Veterans and their families, providers, and community partners. Educational handout: brief educational handout on Parkinson's disease that is available in the VA's "Healthwise for Life" handbook.

Other: Coordinated care management for Parkinson's disease

Interventions

Nurse care managers will use standardized assessment tools and care coordination protocols to address unmet needs of Veterans with PD, and collaborate with these Veterans and their families, providers, and community partners to manage PD care.

Intervention (Arm 2)Usual Care (Arm 1)

To minimize potential bias from participants' awareness of randomization arm assignment, the investigators will provide to all study participants (intervention arm and usual care arm) on enrollment a brief educational handout on Parkinson's disease that is available in the VA's "Healthwise for Life" handbook (page 273). This information includes a definition of PD, its symptoms, and several suggestions for managing PD such as medications and regular exercise.

Usual Care (Arm 1)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Veteran of the United States of America
  • Receiving health care at one of five Veterans Health Administration medical centers in the southwest United States: Greater Los Angeles, Loma Linda, Long Beach, or San Diego, California, or Las Vegas, Nevada.
  • Diagnosis of Parkinson's disease (PD)
  • At least two ICD-9 diagnostic codes for PD (332.0) in the administrative data from October 1, 2010 - to present date or until recruitment target is met
  • At least 18 years of age
  • Must demonstrate capacity to provide consent for study participation.

You may not qualify if:

  • Any Veteran who is a study subject in the Deep Brain Stimulation (DBS) VA cooperative study as these subjects are not to enroll in any other study per DBS study protocol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

VA Loma Linda Healthcare System, Loma Linda, CA

Loma Linda, California, 92357, United States

Location

VA Long Beach Healthcare System, Long Beach, CA

Long Beach, California, 90822, United States

Location

VA San Diego Healthcare System, San Diego, CA

San Diego, California, 92161, United States

Location

VA Greater Los Angeles Healthcare System, West Los Angeles, CA

West Los Angeles, California, 90073, United States

Location

VA Southern Nevada Healthcare System, North Las Vegas, NV

Las Vegas, Nevada, 89106, United States

Location

Related Publications (5)

  • Connor K, Cheng E, Siebens HC, Lee ML, Mittman BS, Ganz DA, Vickrey B. Study protocol of "CHAPS": a randomized controlled trial protocol of Care Coordination for Health Promotion and Activities in Parkinson's Disease to improve the quality of care for individuals with Parkinson's disease. BMC Neurol. 2015 Dec 15;15:258. doi: 10.1186/s12883-015-0506-y.

  • Connor KI, Siebens HC, Mittman BS, Ganz DA, Barry F, McNeese-Smith DK, Cheng EM, Vickrey BG. Implementation fidelity of a nurse-led RCT-tested complex intervention, care coordination for health promotion and activities in Parkinson's disease (CHAPS) in meeting challenges in care management. BMC Neurol. 2022 Jan 24;22(1):36. doi: 10.1186/s12883-021-02481-5.

  • Connor KI, Siebens HC, Mittman BS, McNeese-Smith DK, Ganz DA, Barry F, Edwards LK, McGowan MG, Cheng EM, Vickrey BG. Stakeholder perceptions of components of a Parkinson disease care management intervention, care coordination for health promotion and activities in Parkinson's disease (CHAPS). BMC Neurol. 2020 Dec 2;20(1):437. doi: 10.1186/s12883-020-02011-9.

  • Connor KI, Siebens HC, Mittman BS, Ganz DA, Barry F, Ernst EJ, Edwards LK, McGowan MG, McNeese-Smith DK, Cheng EM, Vickrey BG. Quality and extent of implementation of a nurse-led care management intervention: care coordination for health promotion and activities in Parkinson's disease (CHAPS). BMC Health Serv Res. 2020 Aug 10;20(1):732. doi: 10.1186/s12913-020-05594-8.

  • Connor KI, Cheng EM, Barry F, Siebens HC, Lee ML, Ganz DA, Mittman BS, Connor MK, Edwards LK, McGowan MG, Vickrey BG. Randomized trial of care management to improve Parkinson disease care quality. Neurology. 2019 Apr 16;92(16):e1831-e1842. doi: 10.1212/WNL.0000000000007324. Epub 2019 Mar 22.

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Limitations and Caveats

Study implemented within the Veterans Administration

Results Point of Contact

Title
Eric M Cheng
Organization
VA Greater Los Angeles Healthcare System

Study Officials

  • Karen Connor, PhD RN MBA

    VA Greater Los Angeles Healthcare System, West Los Angeles, CA

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 13, 2012

First Posted

February 15, 2012

Study Start

July 9, 2012

Primary Completion

January 31, 2017

Study Completion

April 30, 2017

Last Updated

March 8, 2019

Results First Posted

March 8, 2019

Record last verified: 2019-03

Data Sharing

IPD Sharing
Will not share

Locations