The Effect of Oxygen Administration on Regional Cerebral Oxygen Saturation (rSO2) in the Non-block Side After Stellate Ganglion Block

NCT01532713 | Completed

• 1 other identifier: 4-2011-0358
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

Stellate ganglion block (SGB) is known to increase blood flow to the innervation area of the stellate ganglion. Near infrared spectroscopy reflects changes of blood volume and allows continuous, non-invasive, and bedside monitoring of regional cerebral oxygen saturation (rSO2). Previous studies have shown the increment of the rSO2 on the block side from the baseline and the decrement of the rSO2 on the non-block side after SGB. Patients with cerebral vascular disease undergoing SGB might be at risk a decrease in cerebral blood flow in the non-block side. The investigators researched the effect of oxygen administration on rSO2 in the non-block side using a near infrared spectroscopy after SGB. 5 L/min oxygen was supplied via nasal cannula from 15 minutes after SGB. The rSO2 in the non-block side were measured before SGB and 5, 10, 15, 20, 25 and 30 minutes after SGB. The present study suggests that oxygen administration can increase the rSO2 of non-block side. In conclusion, it is our belief that oxygen supplement is helpful to the patient with cerebral vascular disease during SGB.

Conditions

SSNHL(Sudden Sensory Neural Hearing Loss)

Outcome Measures

Primary Outcomes (1)

• increase on the regional cerebral oxygen saturation

  The rSO2 on the non-block side after SGB and additional oxygen administration will be compared with the baseline rSO2.

  5 minutes after oxygen administration

Study Arms (1)

non-block side

EXPERIMENTAL

Procedure: oxygen administration

Interventions

oxygen administration PROCEDURE

nasal O2 5L/min via nasal cannula

non-block side

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ages between 20 and 70 years
• ASA PS 1,2
• disease entity : pain in the head, neck, upper extremity, and SSNHL ( sudden sensory neural hearing loss )

You may not qualify if:

• patient with the tendency to bleed
• patient who had cerebrovascular disease
• patient with respiratory disease ( COPD: chronic obstructive lung disease )
• patients who do not give written informed consent to participate in the study

Sponsors & Collaborators

• Yonsei University: lead

Study Sites (1)

Severance Hospital

Seoul, Seoul, 120-752, South Korea

Location

Related Publications (2)

• Park HM, Kim TW, Choi HG, Yoon KB, Yoon DM. The change in regional cerebral oxygen saturation after stellate ganglion block. Korean J Pain. 2010 Jun;23(2):142-6. doi: 10.3344/kjp.2010.23.2.142. Epub 2010 May 31.

  PMID: 20556217 BACKGROUND

• Kim EM, Yoon KB, Lee JH, Yoon DM, Kim DH. The effect of oxygen administration on regional cerebral oxygen saturation after stellate ganglion block on the non-blocked side. Pain Physician. 2013 Mar-Apr;16(2):117-24.

  PMID: 23511678 DERIVED

MeSH Terms

Interventions

Oxygen

Intervention Hierarchy (Ancestors)

Chalcogens; Elements; Inorganic Chemicals; Gases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 8, 2012
• First Posted: February 14, 2012
• Study Start: January 1, 2012
• Primary Completion: December 1, 2012
• Study Completion: March 1, 2013
• Last Updated: March 5, 2014

Record last verified: 2014-03

Locations

KR (1)