Randomized Controlled Trial of eScreen for Problematic Drug Use

NCT01532388 | Completed Results

• 1 other identifier: 2008/308-31/5D
• Study Type: interventional
• Target: 202
• Locations: 1 country
• Sites: 1

Brief Summary

Objectives: This study compared the efficacy of eScreen in a two-armed randomized controlled design, measuring outcomes in terms of changes in problematic drug use up to one year after study recruitment. The eScreen brief Internet intervention for problematic alcohol and drug use offers self-screening, in-depth self-reporting, personalized feedback and treatment recommendations as well as an electronic diary. Progress over time is shown in diagrams detailing consumption levels. Method: Participants with only problematic drug use according to the Drug Use Disorders Identification Test (DUDIT),(DUDIT \>0 for both men and women) or both problematic alcohol use according to the Alcohol Use Disorders Identification Test (AUDIT), (AUDIT \>7 for men and AUDIT \>5 for women) and drug use were randomized to T1 (n=101) or the control group (n=101). Outcomes on alcohol and/or drug use as well as health-related symptoms were assessed after 3, 6 and 12 months. Hypotheses that were tested in this study are 1) that both groups would reduce their drug consumption and drug-related problems at follow-ups compared to the baseline level and 2) that participants in the eScreen group would reduce their drug consumption and drug-related problems to a higher extent than participants in the control group (no intervention) at follow-ups.

Conditions

Problematic AOD Use

Keywords

Randomized Controlled Trial; Alcohol; Drugs; Internet; Screening; Brief intervention

Outcome Measures

Primary Outcomes (1)

• Drug Use Disorders Identification Test-Consumption (DUDIT-C)

  The primary outcome measure for this trial was the total DUDIT score for the first four DUDIT questions at 3-month follow-up, as a measure of drug consumption only, referred to as the DUDIT-C.The DUDIT-C is a measure including the first four items of the DUDIT, with a minimum score of 0 and a maximum score of 16. Higher scores mean a worse outcome. Regarding the DUDIT-C, you will find information on it in the following articles. Please note that the analyses all refer to the same sample from a randomized controlled trial. Apart from the data in the two articles describing results from the current study, there are additional analyses shown in: Berman, A. H., Wennberg, P., \& Sinadinovic, K. (2015). Changes in Mental and Physical Well-Being Among Problematic Alcohol and Drug Users in 12-Month Internet-Based Intervention Trials. Psychology of Addictive Behaviors, 29(1), 97-105. doi: 10.1037/a0038420 A higher score means a worse outcome.

  3 months

Secondary Outcomes (11)

• Drug Use Disorders Identification Test (DUDIT)

  3 months

• Alcohol Use Disorders Identification Test - Consumption (AUDIT-C)

  3 months

• Alcohol Use Disorders Identification Test - AUDIT

  3 months

• Drug Use Disorders Identification Test-Consumption (DUDIT-C)

  6 months

• Drug Use Disorders Identification Test (DUDIT)

  6 months

Study Arms (2)

eScreen

EXPERIMENTAL

Web based self-monitoring of problematic alcohol and drug use.

Behavioral: eScreen

Control group

NO INTERVENTION

Untreated control group

Interventions

eScreen BEHAVIORAL

Web based self-monitoring of problematic alcohol and drug use.

eScreen

Eligibility Criteria

• Age: 15 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• DUDIT \>0

You may not qualify if:

• DUDIT = 0

Sponsors & Collaborators

• Karolinska Institutet: lead

Study Sites (1)

Karolinska institutet, Department of Clinical Neurosciene

Stockholm, 17176, Sweden

Location

Related Publications (4)

• Sinadinovic K, Berman AH, Hasson D, Wennberg P. Internet-based assessment and self-monitoring of problematic alcohol and drug use. Addict Behav. 2010 May;35(5):464-70. doi: 10.1016/j.addbeh.2009.12.021. Epub 2010 Jan 4.

  PMID: 20092953 BACKGROUND

• Sinadinovic K, Wennberg P, Berman AH. Population screening of risky alcohol and drug use via Internet and Interactive Voice Response (IVR): a feasibility and psychometric study in a random sample. Drug Alcohol Depend. 2011 Mar 1;114(1):55-60. doi: 10.1016/j.drugalcdep.2010.09.004. Epub 2010 Oct 27.

  PMID: 21030164 BACKGROUND

• Sinadinovic K, Wennberg P, Berman AH. Targeting problematic users of illicit drugs with Internet-based screening and brief intervention: a randomized controlled trial. Drug Alcohol Depend. 2012 Nov 1;126(1-2):42-50. doi: 10.1016/j.drugalcdep.2012.04.016. Epub 2012 May 20.

  PMID: 22613182 RESULT

• Sinadinovic K, Wennberg P, Berman AH. Internet-based screening and brief intervention for illicit drug users: a randomized controlled trial with 12-month follow-up. J Stud Alcohol Drugs. 2014 Mar;75(2):313-8. doi: 10.15288/jsad.2014.75.313.

  PMID: 24650825 RESULT

Related Links

• Anne H Berman's profile at Uppsala University
• Web based self-monitoring site

Results Point of Contact

• Title: Dr Kristina Sinadinovic
• Organization: Karolinska Institutet

kristina.sinadinovic@socialstyrelsen.se

+46812345735

Study Officials

• Anne H Berman, PhD

  Karolinska Institutet

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Affiliated Researcher

Study Record Dates

• First Submitted: October 27, 2011
• First Posted: February 14, 2012
• Study Start: September 1, 2009
• Primary Completion: April 1, 2011
• Study Completion: May 1, 2012
• Last Updated: November 13, 2023
• Results First Posted: September 29, 2020

Record last verified: 2023-11

Locations

SE (1)