NCT01529814

Brief Summary

Integration success rates measured by resistance to countertorque testing will be higher for the experimental implant design than for the control implants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2011

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2011

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

February 7, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 9, 2012

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

March 28, 2022

Status Verified

March 1, 2022

Enrollment Period

5.4 years

First QC Date

February 7, 2012

Last Update Submit

March 24, 2022

Conditions

Keywords

edentulismdental implantsclinical studyNanotite Certain Tapered implantrandomizedcrestal bone levelearly loading

Outcome Measures

Primary Outcomes (1)

  • Primary stability countertorque measures

    Resistance to countertorque measures showing primary stability success of implants

    2 months

Secondary Outcomes (1)

  • Cumulative success rate

    2 years

Study Arms (2)

New abutment connection implant

EXPERIMENTAL

Implant with new abutment connection

Device: Implant with new abutment connection

Nanotite Certain Tapered implant

ACTIVE COMPARATOR

Nanotite Certain Tapered (standard abutment connection) implant

Device: Nanotite Certain Tapered implant

Interventions

New abutment connection implant system

Also known as: Osseotite Endosseous dental implant
New abutment connection implant

Nanotite Certain Tapered (standard abutment connection) implant

Also known as: Nanotite endosseous dental implant
Nanotite Certain Tapered implant

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients of either sex and older than 18 years of age
  • patients needing at least one dental implant to treat partial edentulism
  • patients physically able to tolerate surgical and restorative dental procedures
  • patients agreeing to all protocol visits

You may not qualify if:

  • patients with infection or severe inflammation at the intended treatment sites
  • patients smoking greater than 10 cigarettes per day
  • patients with uncontrolled diabetes mellitus
  • patients with uncontrolled metabolic diseases
  • patients who received radiation treatment to the head in the past 12 months
  • patients needing bone grafting at the intended treatment sites
  • patients known to be pregnant at screening visit
  • patients with para-functional habits like bruxing and clenching

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad Mayor

Santiago, Chile

Location

MeSH Terms

Conditions

Tooth Diseases

Interventions

Mutagenesis, Insertional

Condition Hierarchy (Ancestors)

Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Protein EngineeringGenetic EngineeringGenetic TechniquesInvestigative TechniquesMutationGenetic VariationGenetic PhenomenaMutagenesis

Study Officials

  • Carlos Montoya, DDS

    Universidad Mayor

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 7, 2012

First Posted

February 9, 2012

Study Start

July 1, 2011

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

March 28, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations