NCT01522274

Brief Summary

This research study is for FEMALE cigarette smokers who want to quit smoking. Participants will be provided with brief quit-smoking education at the beginning of the study and will receive the nicotine patch for 10 weeks, free of charge. Participants will be assigned to either an exercise program or a general health education program. The exercise and health education programs will take place over 14 weeks, with follow-up appointments 3, 6, and 12 months after the end of the 14-week program. There is no fee for any part of this study and participants will be compensated for their time.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
113

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

January 18, 2012

Completed
13 days until next milestone

First Posted

Study publicly available on registry

January 31, 2012

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2017

Completed
Last Updated

August 1, 2017

Status Verified

July 1, 2017

Enrollment Period

5.5 years

First QC Date

January 18, 2012

Last Update Submit

July 28, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Smoking Cessation

    Verified by saliva cotinine

    7-Day Point Prevalence at 3, 6, 9 and 1-year follow-ups

Secondary Outcomes (1)

  • Cognitive and Affective Mechanisms of Treatment

    Daily assessments completed throughout the day at random and scheduled times from baseline to 3 months

Study Arms (2)

Moderate intensity exercise

ACTIVE COMPARATOR

Brisk walk on treadmill for 56 minutes 3x per week.

Behavioral: Moderate intensity exercise

Health education

ACTIVE COMPARATOR

Attend health education sessions 3x per week.

Behavioral: Health education

Interventions

Brisk walking on a treadmill for 56 minutes 3x per week.

Moderate intensity exercise

Videos

Health education

Eligibility Criteria

Age18 Years - 55 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Current smoker

You may not qualify if:

  • Ineligible after telephone screen.
  • Each participant's personal physician/clinic determines it is unsafe to participate.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Public Health Building @ 121 South Main St

Providence, Rhode Island, 02912, United States

Location

Related Publications (1)

  • LaRowe LR, Dunsiger SI, Williams DM. Acute exercise-induced changes in motivation and behavioral expectation for quitting smoking as predictors of smoking behavior in women. Psychol Addict Behav. 2023 May;37(3):475-482. doi: 10.1037/adb0000901. Epub 2022 Dec 1.

MeSH Terms

Conditions

Cigarette Smoking

Condition Hierarchy (Ancestors)

Tobacco SmokingSmokingBehaviorTobacco Use

Study Officials

  • David Williams, PhD

    Brown University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

January 18, 2012

First Posted

January 31, 2012

Study Start

January 1, 2012

Primary Completion

July 1, 2017

Study Completion

July 1, 2017

Last Updated

August 1, 2017

Record last verified: 2017-07

Locations