NCT01521442

Brief Summary

The primary objective of the current study is to establish the safety and acceptability of Mindful Yoga Therapy as an adjunctive treatment for posttraumatic stress disorder (PTSD) among Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) Veterans. The current study also seeks to establish preliminary efficacy of Mindful Yoga Therapy for reduction of symptoms of PTSD and explore heart rate variability as a mechanism of therapeutic action.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 2013

Typical duration for phase_1

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 19, 2012

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 30, 2012

Completed
1.2 years until next milestone

Study Start

First participant enrolled

April 1, 2013

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

December 19, 2014

Status Verified

December 1, 2014

Enrollment Period

2.4 years

First QC Date

January 19, 2012

Last Update Submit

December 18, 2014

Conditions

Keywords

PTSDYogaComplementary and Alternative Medicine (CAM)

Outcome Measures

Primary Outcomes (1)

  • Clinician Administered PTSD Scale (CAPS)

    The "gold standard" measure of frequency and intensity of PTSD symptoms.

    12 weeks

Study Arms (2)

Arm 1

EXPERIMENTAL

12 sessions of Mindful Yoga Therapy delivered two times per week for 75 minutes each.

Behavioral: Mindful Yoga Therapy

Arm 2

OTHER

12-week delay before beginning Mindful Yoga Therapy treatment which will consist of 12 sessions of Mindful Yoga Therapy delivered two times per week for 75 minutes each.

Behavioral: Wait-list Control

Interventions

Veterans will participate in twice weekly Mindful Yoga Therapy, which includes meditation, breathing practices, mindful movement, and guided rest (yoga nidra), as well as daily home practice.

Arm 1

Participants will receive Mindful Yoga Therapy intervention after 12 weeks from being enrolled. Veterans will participate in twice weekly Mindful Yoga Therapy, which includes meditation, breathing practices, mindful movement, and guided rest (yoga nidra), as well as daily home practice.

Arm 2

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • OEF/OIF/OND Veteran
  • Ages 18-45
  • Currently enrolled in active PTSD treatment
  • Meet criteria for PTSD
  • Veteran with combat exposure during deployment

You may not qualify if:

  • Current psychotic disorder or bipolar disorder
  • Current use of beta-blocker medication
  • Current regular yoga or meditation practice in the past month
  • Significant limitations or injuries

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Connecticut Healthcare System

West Haven, Connecticut, 06516, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Officials

  • Alicia Heapy, Ph.D.

    VA Connecticut Healthcare System

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 19, 2012

First Posted

January 30, 2012

Study Start

April 1, 2013

Primary Completion

September 1, 2015

Study Completion

November 1, 2015

Last Updated

December 19, 2014

Record last verified: 2014-12

Locations