LIFE Cancer Survivorship Database for Pediatric Cancer
A Research Database for Survivors of Childhood Cancer
1 other identifier
observational
5,000
1 country
1
Brief Summary
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes. Using clinical information obtained from follow-up visits of childhood cancer survivors, the database will focus on interventions to improve health status and health-related quality of life in childhood cancer survivors. This study allows for establishment and analyses of a research database for LIFE survivors by the investigators listed herein. Over the last three decades, there has been marked improvement in survival following childhood cancer, with 5-year survival rates now approaching 80%. However, the use of cancer therapy at an early age can result in complications that may not be apparent until years later as the child matures. These resulting complications, called late effects, are principally related to the specific therapy employed and the age of the child at the time the therapy was administered. Late effects may affect virtually every body system and substantially impair quality of life. As many as two-thirds of childhood cancer survivors develop at least one late effect as a result of treatment, and approximately one-third have a late effect classified as severe or life threatening.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2009
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2009
CompletedFirst Submitted
Initial submission to the registry
January 11, 2012
CompletedFirst Posted
Study publicly available on registry
January 26, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2050
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2050
June 13, 2022
August 1, 2021
40.9 years
January 11, 2012
June 9, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
create a database of Cancer Survivors
To use the information gained from this assessment for identification of risk factors and populations at risk, and to develop interventions to improve health status and quality of life (QOL) in childhood cancer survivors.
Annual (up to 40 years)
Study Arms (1)
Eligible Population
Cancer Survivors of all ages (Must be diagnosed with cancer at 21 years or younger)
Eligibility Criteria
Population diagnosed with cancer at 21 years of age or younger
You may qualify if:
- Been diagnosed with cancer or similar disease
- Been diagnosed with cancer at 21 years of age or younger
- Be currently off treatment and disease free
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
Related Links
MeSH Terms
Conditions
Study Officials
- PRINCIPAL INVESTIGATOR
David Freyer, DO, MS
Children's Hospital Los Angeles
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director, LIFE Cancer Survivorship and Transition Program
Study Record Dates
First Submitted
January 11, 2012
First Posted
January 26, 2012
Study Start
February 1, 2009
Primary Completion (Estimated)
January 1, 2050
Study Completion (Estimated)
December 1, 2050
Last Updated
June 13, 2022
Record last verified: 2021-08