NCT01517607

Brief Summary

This non-interventional study examines whether the patient's level of information and the consideration of the patient's preference have a positive effect on the compliance and thus also on the therapeutic success.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
506

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2012

Geographic Reach
1 country

149 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 20, 2012

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 25, 2012

Completed
7 days until next milestone

Study Start

First participant enrolled

February 1, 2012

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
Last Updated

October 1, 2015

Status Verified

September 1, 2015

Enrollment Period

1.8 years

First QC Date

January 20, 2012

Last Update Submit

September 30, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Patient compliance: Measured by patient response to a questionnaire

    Month 0 - Month 12

Secondary Outcomes (6)

  • Patient's level of information: Measured by patient response to a questionnaire

    Month 0 - Month 12

  • Patient's preference for the oral pharmaceutical form: Measured by patient response to a questionnaire

    Month 0 - Month 12

  • Reasons for the therapeutic decision of the physician: Measured by physician responses

    Month 0

  • Laboratory parameters of predefined blood measurements

    Month 0- Month 12

  • Ulcerative Colitis Disease Activity Index (UCDAI)

    Month 0 - Month 12

  • +1 more secondary outcomes

Study Arms (1)

Mesalazine

Other: Mesalazine

Interventions

Patient's treated with oral Mesalazine

Mesalazine

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Primary care facilities

You may qualify if:

  • Patients are treated for the first time with oral PENTASA®, e.g. following first diagnosis of ulcerative colitis for treatment of an acute episode or
  • Following a therapy-free period (no previous mesalazine therapy) or due to poor response or underdosage oder lacking acceptance of the previous medication the patients are re-adjusted to oral PENTASA®,
  • The patients (≥ 18 years) have been informed about the NIS and have given their written consent for participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (149)

Investigational site, Wettinerstraße 22

Altenburg, Germany

Location

Investigational site, Marienstraße 6

Amberg, Germany

Location

Investigational site, Adam-Ries-Straße 57c

Annaberg-Buchholz, Germany

Location

Investigational site, Goethestraße 5

Ansbach, Germany

Location

Investigational site, Elisenstraße 32

Aschaffenburg, Germany

Location

Investigational site, Prinzregentenstraße 8

Augsburg, Germany

Location

Investigational site, Koblenzer Straße 37

Bad Godesberg, Germany

Location

Investigational site, Goethestraße 15g

Bad Neustadt an der Saale, Germany

Location

Investigational site, Töpferstraße 17

Bautzen, Germany

Location

Investigational site, Bahnhofstraße 18

Berlin, Germany

Location

Investigational site, Blankenburger Chaussee 86

Berlin, Germany

Location

Investigational site, Bundesallee 104-105

Berlin, Germany

Location

Investigational site, Ehrenfelsstraße 47

Berlin, Germany

Location

Investigational site, Etkar-Andre-Straße 8

Berlin, Germany

Location

Investigational site, Hohenzollerndamm 47a

Berlin, Germany

Location

Investigational site, Innsbrucker Straße 58

Berlin, Germany

Location

Investigational site, Klosterstraße 34

Berlin, Germany

Location

Investigational site, Kurfürstendamm 42

Berlin, Germany

Location

Investigational site, Mohrenstraße 6

Berlin, Germany

Location

Investigational site, Myslowitzer Straße 49

Berlin, Germany

Location

Investigational site, Schönhauser Allee 118

Berlin, Germany

Location

Investigational site, Schönhauser Allee 129

Berlin, Germany

Location

Investigational site, Schönstraße 90

Berlin, Germany

Location

Investigational site, Treskowallee 99

Berlin, Germany

Location

Investigational site, Hauptstraße 88

Bielefeld, Germany

Location

Investigational site, Hauptstraße 9

Bietigheim-Bissingen, Germany

Location

Investigational site, Kasernenstraße 22-24

Bonn, Germany

Location

Investigational site, Münsterstraße 18

Bonn, Germany

Location

Investigational site, Propst-Sievert-Weg 9

Borken, Germany

Location

Investigational site, Trauerberg 27-28

Brandenburg/Havel, Germany

Location

Investigational site, Wetzlarer Straße 22

Butzbach, Germany

Location

Investigational site, Hermann-Hesse-Platz 3

Calw, Germany

Location

Investigational site, Dortmunder Straße

Castrop-Rauxl, Germany

Location

Investigational site, Hainstraße 112

Chemnitz, Germany

Location

Investigational site, Graseggerstraße 105

Cologne, Germany

Location

Investigational site, Venloer Straße 247

Cologne, Germany

Location

Investigational site, Bahnhofstraße 64

Cottbus, Germany

Location

Investigational site, Vetschauer Straße 11a

Cottbus, Germany

Location

Investigational site, Frankfurter Straße 3

Darmstadt, Germany

Location

Investigational site, Rheinstraße 44-46

Darmstadt, Germany

Location

Investigational site, Lagesche Straße 19

Detmold, Germany

Location

Investigational site, Jahnstraße 1

Dingolfing, Germany

Location

Investigational site, Karlsbader Straße 7

Dinkelsbühl, Germany

Location

Investigational site, Recklinghäuser Straße 14

Dorsten, Germany

Location

Investigational site, Rheinlanddamm 10

Dortmund, Germany

Location

Investigational site, Lukasstraße 3

Dresden, Germany

Location

Investigational site, Rehefelder Straße 12

Dresden, Germany

Location

Investigational site, Mühlhäuser Straße 94, Haus F

Eisenach, Germany

Location

Investigational site, Winkelgasse 1

Ellefeld, Germany

Location

Investigational site, Königstraße 12-14

Elmshorn, Germany

Location

Investigational site, Märkischestraße 30

Engelskirchen, Germany

Location

Investigational site, Franz-Busbach-Straße 8

Erftstadt, Germany

Location

Investigational site, Neuwerkstraße 2

Erfurt, Germany

Location

Investigational site, Ruhrallee 81

Essen, Germany

Location

Investigational site, Viktoriastraße 5

Euskirchen, Germany

Location

Investigational site, Im Prüfling 23

Frankfurt, Germany

Location

Investigational site, Hochstraße 43

Frankfurt am Main, Germany

Location

Investigational site, Pfingsweidstraße 4

Frankfurt am Main, Germany

Location

Investigational site, Stresemannallee 3

Frankfurt am Main, Germany

Location

Investigational site, Habsburgerstraße 105

Freiburg im Breisgau, Germany

Location

Investigational site, Schnetzenhauser Straße 5

Friedrichshafen, Germany

Location

Investigational site, Moststraße 19

Fürth, Germany

Location

Investigational site, Gartenstraße 29

Gardelegen, Germany

Location

Investigational site, Hauptstraße 60-64

Garmisch-Partenkirchen, Germany

Location

Investigational site, Am Markt 3

Gehrden, Germany

Location

Investigational site, In der Heide 19

Gelsenkirchen, Germany

Location

Investigational site, Von-der-Recke-Straße 14

Gelsenkirchen, Germany

Location

Investigational site, Pollinger Straße 23

Gilching, Germany

Location

Investigational site, Von-Werth-Straße 5

Grevenbroich, Germany

Location

Investigational site, Avenwedder Straße 50

Gütersloh, Germany

Location

Investigational site, Hachelweg 19

Hachelweg 19, Germany

Location

Investigational site, Fürstin-Eugenie-Straße 7

Hachingen, Germany

Location

Investigational site, Buscheystraße 15a

Hagen, Germany

Location

Investigational site, Eppendorfer Baum 35-37

Hamburg, Germany

Location

Investigational site, Eppendorfer Landstraße 42

Hamburg, Germany

Location

Investigational site, Fontenay 1d

Hamburg, Germany

Location

Investigational site, Harksheider Straße 3

Hamburg, Germany

Location

Investigational site, Schlossstrasse 44

Hamburg, Germany

Location

Investigational site, Schäferkampsallee 56-58

Hamburg, Germany

Location

Investigational site, Sudetenweg 6

Hamm, Germany

Location

Investigational site, Staufenbergstraße 31

Heilbronn, Germany

Location

Investigational site, Frankfurter Straße 100a

Hennef (Sieg), Germany

Location

Investigational site, Am Ruschenhof 24

Herne, Germany

Location

Investigational site, Wiescherstraße 20

Herne, Germany

Location

Investigational site, Seestraße 43

Herrsching am Ammersee, Germany

Location

Investigational site, Waisenhausstraße 2

Iserlohn, Germany

Location

Investigational site, J.-Lange-straße 20

Jerichow, Germany

Location

Investigational site, Prinzenallee 10

Jever, Germany

Location

Investigational site, Hans-Sachs-Straße 1

Karlsruhe, Germany

Location

Investigational site, Am Tiefen Weg 2

Karlstadt am Main, Germany

Location

Investigational site, Opernstraße 9

Kassel, Germany

Location

Investigational site, Feldstraße 5-7

Kiel, Germany

Location

Investigational site, Moltkestraße 9

Kitzingen, Germany

Location

Investigational site, Herzog-Adolph-Straße 13

Königstein, Germany

Location

Investigational site, Schalaunische Straße 6-7

Köthen, Germany

Location

Investigational site, Dreifaltigkeitsplatz 177

Landshut, Germany

Location

Investigational site, Röntgenstraße 6-8

Langen, Germany

Location

Investigational site, Funkenburgstraße 19

Leipzig, Germany

Location

Investigational site, Johannisplatz 1

Leipzig, Germany

Location

Investigational site, Markt 3

Leisnig, Germany

Location

Investigational site, Am Gesundheitspark 11

Leverkusen, Germany

Location

Investigational site, Yorckstraße 1

Ludwigshafen, Germany

Location

Investigational site, Kronsforder Allee 19

Lübeck, Germany

Location

Investigational site, Kronsforder Allee 69

Lübeck, Germany

Location

Investigational site, Bismarckplatz 1

Mannheim, Germany

Location

Investigational site, Stiftsweg 17

Mechernich, Germany

Location

Investigational site, Am Harras 2

München, Germany

Location

Investigational site, Irisstraße 23

München, Germany

Location

Investigational site, Kaulbachstraße 61

München, Germany

Location

Investigational site, Maximilianstraße 16

München, Germany

Location

Investigational site, Schönfeldstraße 16

München, Germany

Location

Investigational site, Unterer Markt 26-27

Neumarkt, Germany

Location

Investigational site, Hofgründchen 13

Neuwied, Germany

Location

Investigational site, Am Stadtpark 2

Nuremberg, Germany

Location

Investigational site, Glogauer Straße 42

Nuremberg, Germany

Location

Investigational site, Weiltinger Straße 11

Nuremberg, Germany

Location

Investigational site, Hauptstraße 36

Oldenburg, Germany

Location

Investigational site, Neue Donnerschweer Straße 30

Oldenburg, Germany

Location

Investigational site, Ofener Straße 30

Oldenburg, Germany

Location

Investigational site, Bramscher Straße 242

Osnabrück, Germany

Location

Investigational site, Le-Mans-Wall 5

Paderborn, Germany

Location

Investigational site, Westendstraße 38

Paderborn, Germany

Location

Investigational site, Haptkanal rechts 75

Papenburg, Germany

Location

Investigational site, Neundorfer Straße 14

Plauen, Germany

Location

Investigational site, Allee nach Sanccouci 7

Potsdam, Germany

Location

Investigational site, Großbeerenstraße 301

Potsdam, Germany

Location

Investigational site, R.-Breitscheid-Straße 56

Potsdam, Germany

Location

Investigational site, Kaiserstraße 166

Radevormwald, Germany

Location

Investigational site, Neue Straße 34

Reinsdorf, Germany

Location

Investigational site, Keramikerstraße 61

Rheinbach, Germany

Location

Investigational site, St.-Petersburger-straße 18c

Rostock, Germany

Location

Investigational site, Tegernseerstraße 100

Rottach-Weissach, Germany

Location

Investigational site, Marktplatz 23

Rottenburg, Germany

Location

Investigational site, Waldhausstraße 13

Schmalkalden, Germany

Location

Investigational site, Krankenhausstraße 20

Schwalmstadt, Germany

Location

Investigational site, Virchowstraße 10c

Singen, Germany

Location

Investigational site, Wallstraße 38

Stade, Germany

Location

Investigational site, Am Wallgraben 99

Stuttgart, Germany

Location

Investigational site, Röhre 1

Sundern, Germany

Location

Investigational site, Straße des Friedens 34c

Teuchern, Germany

Location

Investigational site, Hambrocker Straße 53

Uelzen, Germany

Location

Investigational site, Andreaestraße 16/1

Vahingen, Germany

Location

Investigational site, Hochstraße 20

Waltrop, Germany

Location

Investigational site, Kletzstraße 13B

Waren, Germany

Location

Investigational site, Fischergasse 16

Weilheim, Germany

Location

Investigational site, Julius-Leber-Strasße 8

Wesel, Germany

Location

Investigational site, Westring 14

Wesseling, Germany

Location

Investigational site, Forsthausstraße 1e

Wetzlar, Germany

Location

Investigational site, Berliner Straße 8

Wittenberg, Germany

Location

MeSH Terms

Conditions

Colitis, Ulcerative

Interventions

Mesalamine

Condition Hierarchy (Ancestors)

ColitisGastroenteritisGastrointestinal DiseasesDigestive System DiseasesInflammatory Bowel DiseasesColonic DiseasesIntestinal Diseases

Intervention Hierarchy (Ancestors)

meta-AminobenzoatesAminobenzoatesBenzoatesAcids, CarbocyclicCarboxylic AcidsOrganic ChemicalsAminosalicylic AcidsSalicylatesHydroxybenzoatesHydroxy AcidsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsPhenols

Study Officials

  • Clinical Development Support

    Ferring Pharmaceuticals

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 20, 2012

First Posted

January 25, 2012

Study Start

February 1, 2012

Primary Completion

December 1, 2013

Study Completion

December 1, 2013

Last Updated

October 1, 2015

Record last verified: 2015-09

Locations