Genetics and Phantom Limb Pain
Integrative Genomic Analysis In Phantom Limb Pain
Integrative Genomic Analysis In Phantom Limb Pain
Sponsor study identifier
Secondary identifiers
observational
0
0 countries
N/A
Study Start
January 3, 2012
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
July 30, 2014
Date type not reportedThis date has not been verified as actual or estimated.
Background: \- Many people who lose a limb feel pain in the missing limb. This feeling is called phantom limb pain. Researchers do not fully understand what causes this pain. Differences in people's genes may play a role. Comparing the genes of people with and without phantom limb pain may help researchers better understand this feeling, who is likely to develop it, and how to treat it. Objectives: \- To study whether genetic differences affect phantom limb pain. Eligibility: \- Individuals at least 18 years of age who have lost an arm or leg at least 3 months ago. Design:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 30, 2014
Date type not reportedThis date has not been verified as actual or estimated.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 3, 2012
Date type not reportedThis date has not been verified as actual or estimated.
January 24, 2012
Actual (reported)January 25, 2012
Actual (reported)July 30, 2014
Date type not reportedThis date has not been verified as actual or estimated.
SNP frequency between PLP and non-PLP group
Gene expression profile between PLP and non-PLP group
Epigenetic profile between PLP and non-PLP group
Weinstein SM. Phantom limb pain and related disorders. Neurol Clin. 1998 Nov;16(4):919-36. doi: 10.1016/s0733-8619(05)70105-5.
Sherman RA, Sherman CJ. Prevalence and characteristics of chronic phantom limb pain among American veterans. Results of a trial survey. Am J Phys Med. 1983 Oct;62(5):227-38.
Montoya P, Larbig W, Grulke N, Flor H, Taub E, Birbaumer N. The relationship of phantom limb pain to other phantom limb phenomena in upper extremity amputees. Pain. 1997 Aug;72(1-2):87-93. doi: 10.1016/s0304-3959(97)00004-3.
Hyungsuk Kim, D.D.S.
National Institute of Nursing Research (NINR)
0 participants (actual enrollment reported by the registry).
First Submitted
January 24, 2012
First Posted
January 25, 2012
Study Start
January 3, 2012
Date type not reportedThis date has not been verified as actual or estimated.
Nitric Oxide and Sickle Cell Pain
Contact the study team to confirm eligibility.
Study Completion
July 30, 2014
Date type not reportedThis date has not been verified as actual or estimated.
Last Updated
December 12, 2019
Record last verified: 2014-07-30
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Source: ClinicalTrials.gov.
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