Length of Stay and Complications in High-risk Patients Receiving Fast-track Total Hip (THA) or Knee- Alloplasty (TKA)
1 other identifier
observational
60,000
1 country
7
Brief Summary
The purpose of the study is to determine the influence of preoperative co-morbidity in relation to increased length of stay and postoperative complications in patients receiving fast-track hip or knee replacement.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2010
Longer than P75 for all trials
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2010
CompletedFirst Submitted
Initial submission to the registry
January 18, 2012
CompletedFirst Posted
Study publicly available on registry
January 24, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2019
CompletedJune 22, 2021
June 1, 2021
8.9 years
January 18, 2012
June 20, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Length of hospital stay and reasons for length of hospital stay >4days
Number of nights spend in hospital after day of surgery, including transferral between departments. Any procedure followed by more than 4 days in hospital will have review of discharge papers to determine causes of the "prolonged" admission
At discharge
Surgically related readmissions
Evaluation of any potentially surgery related readmission 90 days after discharge. Readmissions defined as related are defined as: Revision due to prosthesis problems, deep venous thrombosis (DVT), pulmonary embolism (PE) (verified or disproved), stroke/transitory cerebral ischaemia (TCI), possible wound infection (return to operating theatre, treatment with antibiotics only, no treatment), fractures without known trauma, falls, knee manipulation, hip dislocation, cardiac problems (acute myocardial infarction (AMI), any type of arrhythmia), pneumonia, urinary retention (UR), abdominal complications (gastric ulcer, ileus) and sequelae (rehabilitation, opioid side-effects, pain, other conditions related to surgery). Readmissions due to chronic obstructive lung disease (COPD), syncope and urinary tract infection (UTI) ≤ 30 days of primary admission
90 days after surgery
Secondary Outcomes (1)
Mortality 90 days after surgery
90 days after surgery
Other Outcomes (1)
Co-morbidity related readmissions
90 days after surgery
Study Arms (1)
Fast-track THA/TKA
Any patient receiving THA/TKA in the participating wards
Eligibility Criteria
unselected patients receiving THA or TKA
You may qualify if:
- Standardized elective fast-track THA or TKA
You may not qualify if:
- Elective THA or TKA not in regular fast-track setup
- not a Danish citizen
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Rigshospitalet, Denmarklead
- Hvidovre University Hospitalcollaborator
- Aarhus University Hospitalcollaborator
- Vejle Hospitalcollaborator
- Esbjerg Hospital - University Hospital of Southern Denmarkcollaborator
- Regional Hospital Holstebrocollaborator
- Naestved Hospitalcollaborator
- Bispebjerg Hospitalcollaborator
- Central Jutland Regional Hospitalcollaborator
- Aalborg University Hospitalcollaborator
Study Sites (7)
Himmerland Hospital
Farsø, Judland, 9640, Denmark
Holstebro Regionalhospital
Holstebro, Judland, 7500, Denmark
Vejle Hospital
Vejle, Judland, 7100, Denmark
Hvidovre Hospital
Hvidovre, Region Sjælland, 2650, Denmark
Bispebjerg University Hospital
Copenhagen, Denmark
Gentofte University Hospital
Gentofte Municipality, Denmark
Næstved Hospital
Næstved, Denmark
Related Publications (4)
Ortved M, Petersen PB, Jorgensen CC, Kehlet H; Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Postoperative Morbidity and Mortality in Diabetic Patients After Fast-Track Hip and Knee Arthroplasty: A Prospective Follow-up Cohort of 36,762 Procedures. Anesth Analg. 2021 Jul 1;133(1):115-122. doi: 10.1213/ANE.0000000000005248.
PMID: 33234944DERIVEDJorgensen CC, Gromov K, Petersen PB, Kehlet H; Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Influence of day of surgery and prediction of LOS > 2 days after fast-track hip and knee replacement. Acta Orthop. 2021 Apr;92(2):170-175. doi: 10.1080/17453674.2020.1844946. Epub 2020 Nov 12.
PMID: 33176546DERIVEDPetersen PB, Jorgensen CC, Kehlet H; Lundbeck Foundation Center for Fast-track Hip and Knee Replacement collaborative group. Temporal trends in length of stay and readmissions after fast-track hip and knee arthroplasty. Dan Med J. 2019 Jul;66(7):A5553.
PMID: 31256778DERIVEDJorgensen CC, Petersen MA, Kehlet H; Lundbeck Foundation Centre for Fast-Track Hip and Knee Replacement Collaborative Group. Preoperative prediction of potentially preventable morbidity after fast-track hip and knee arthroplasty: a detailed descriptive cohort study. BMJ Open. 2016 Jan 12;6(1):e009813. doi: 10.1136/bmjopen-2015-009813.
PMID: 26758264DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Christoffer C Joergensen, MD
Rigshospitalet, Denmark
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 90 Days
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Research-fellow
Study Record Dates
First Submitted
January 18, 2012
First Posted
January 24, 2012
Study Start
February 1, 2010
Primary Completion
January 1, 2019
Study Completion
January 1, 2019
Last Updated
June 22, 2021
Record last verified: 2021-06