NCT01512732

Brief Summary

Today, no non-verbal auditory stimuli that assess mental processing are available in Israel. The goal of this study is to make available a validated set of auditory stimuli in Israel. We created a computerized Hebrew version of the Montreal Affective Voices (MAV). The MAV is a novel tool for assessing mental processing. The MAV consists of 90 nonverbal affect bursts corresponding to nine different emotions (such as anger, fear, happiness etc.) recorded by ten different actors. The uniqueness of these affective bursts is that they do not contain verbal context, but rather express affective moods using the vowel /a/ (as in "apple"). In this study, the investigators will verify the new Hebrew version of MAV in healthy control groups. Next, the investigators will compare the mental processing ability in young vs. old population, using the MAV test. In addition, the investigators will assess mental processing in two pathologic study groups (Parkinson's disease, major depressive disorder) using the MAV test. The investigators intend to use the MAV tool in future research in Parkinson's disease and depression.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 15, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 19, 2012

Completed
13 days until next milestone

Study Start

First participant enrolled

February 1, 2012

Completed
Last Updated

January 24, 2012

Status Verified

January 1, 2012

First QC Date

January 15, 2012

Last Update Submit

January 22, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Verifying the results achieved by Belin et al (2008) when using the Hebrew version of the MAV bursts in healthy control groups.

    12 months

Study Arms (3)

healthy control group

Young (20-49) and Older (50-70) healthy group (n=60)

Parkinson's disease patients

(n=30).

Major depressive disorder patients

(n=30).

Eligibility Criteria

Age20 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

healthy group, Parkinson's disease patients, Major depressive disorder patients.

You may qualify if:

  • Healthy group
  • Parkinson's disease
  • Major depressive disorder
  • All participants will be competent and willing to give written informed consent. Patients over 65 and/or suspected to have a cognitive decline will be tested by the Mini-mental test and will be included in the study only if the score is above 26.

You may not qualify if:

  • Non-competent or unable to give written informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah Medical Organization,

Jerusalem, Israel

Location

MeSH Terms

Conditions

Parkinson DiseaseDepression

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative DiseasesBehavioral SymptomsBehavior

Central Study Contacts

Study Design

Study Type
observational
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 15, 2012

First Posted

January 19, 2012

Study Start

February 1, 2012

Last Updated

January 24, 2012

Record last verified: 2012-01

Locations