Electroacupuncture Preconditioning on Geriatric Noncardiac Surgery
Effects of Electroacupuncture Preconditioning on Outcomes of the Geriatric Patients With Coronary Heart Disease Undergoing Non-cardiac Surgery
1 other identifier
interventional
300
1 country
1
Brief Summary
The purpose of this study is to observe whether the electroacupuncture (EA) preconditioning for five days before operation can improve the outcomes of patients with coronary heart disease undergoing geriatric non-cardiac surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2011
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2011
CompletedFirst Submitted
Initial submission to the registry
December 13, 2011
CompletedFirst Posted
Study publicly available on registry
January 11, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2013
CompletedJanuary 11, 2012
February 1, 2011
1.3 years
December 13, 2011
January 8, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The change of myocardial ischemic injury markers,including serum level of c-reactive protein and Troponin I
to observe the change of the level of multiple myocardial ischemic injury markers at the different time points.
10 minutes before EA, 10 minutes pre-operation,the day of post-operation, 24hours post-operation, 72 hours post-operation
Secondary Outcomes (2)
The change of ST segment of EEG at different time points
10 minutes before EA, 10 minutes pre-operation,the day of post-operation, 24hours post-operation, 72 hours post-operation
Cardiac ultrasonic scan
five days pre-operation , five days post-operation
Study Arms (2)
EA preconditioning
EXPERIMENTALelectroacupuncture five days pre-operation
Sham EA preconditioning
SHAM COMPARATORPatients treated with sham EA preconditioning Intervention
Interventions
EA preconditioning group was treated at bilateral Neiguan(PC 6)，Lieque(LU 7)and Yunmen(LU 2)with electrical stimulation(5-30 Hz，2．34-6．24 mA，30 min)for 5 consecutive days before surgery
Patients in Sham EA preconditioning group was treated at bilateral Neiguan(PC 6)，Lieque(LU 7)and Yunmen(LU 2)without electrical stimulation(5-30 Hz，2．34-6．24 mA，30 min)for 5 consecutive days before surgery
Eligibility Criteria
You may qualify if:
- elective abdominal surgery with coronary heart disease
You may not qualify if:
- serious bradycardiac arrythmia
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Xijing Hospitallead
Study Sites (1)
Xijing hospital
Xi'an, Shannxi, 710032, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Shaoyang Chen, M.D.
Xijing Hospital, the Fourth Military Medical University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 13, 2011
First Posted
January 11, 2012
Study Start
February 1, 2011
Primary Completion
June 1, 2012
Study Completion
January 1, 2013
Last Updated
January 11, 2012
Record last verified: 2011-02