NCT01500928

Brief Summary

The Purpose of the study is to to evaluate the performance of the SOLO (version 2.0) micropump insulin delivery system, in Type 1 diabetic patients who use insulin pumps for their treatment.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2011

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

December 11, 2011

Completed
18 days until next milestone

First Posted

Study publicly available on registry

December 29, 2011

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2012

Completed
Last Updated

December 29, 2011

Status Verified

December 1, 2011

Enrollment Period

1 year

First QC Date

December 11, 2011

Last Update Submit

December 25, 2011

Conditions

Keywords

Insulin PumpGlycemic ControlType 1 Diabetes

Outcome Measures

Primary Outcomes (3)

  • Device related safety issues

    Subject complaints documented in the R\&D questionnaire and Complaint Report Forms which were assessed and found to be device related safety issues.

    with in the first month of use

  • SOLO use errors

    Use errors or potential use errors reported in Subject Diary which may be related to SOLO safety.

    within the first month of use

  • Device-related adverse outcome

    Device-related adverse outcome, such as significant skin irritation or infection at the attachment site

    within the first month of use

Secondary Outcomes (3)

  • Diabetes-related adverse outcome

    with in first month of use

  • Satisfaction iwth SOLO

    within the first month of use

  • Product quality (MTBF)

    within the first month of use

Interventions

Use of the SOLO insulin pump for treatment of type 1 diabetes.

Eligibility Criteria

Age16 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Age range:
  • to 65 years (Graz)
  • to 65 years (Israel)
  • Diabetic insulin pump user with diagnosis duration of more than 6 months.
  • Subjects who are using Humalog®, NovoRapid®/NovoLog or Apidra® 100U/ml in- - Measures glucose at least four times per day.
  • No more than one severe hypoglycemic or ketoacidosis episode within one year
  • Willing to sign an informed consent.
  • Cooperative, willing to attend all study visits

You may not qualify if:

  • A1c \>= 10.0%
  • Two or more documented events of severe hypoglycemia within the previous 12 months
  • Diabetes related hospitalization over the past 12 months
  • Current significant diabetes-related complications
  • Pregnant, lactating or planning to become pregnant during the course of the study
  • Substance or alcohol abuse
  • Uncontrolled hypertension
  • Known dermal hypersensitivity to medical adhesive
  • Recurrent episodes of skin infections or dermatological allergies
  • Serious or unstable medical or psychological conditions
  • Current participation in other clinical studies.
  • Working for a competitor company

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Schneider Medical Center

Petah Tikva, Israel

RECRUITING

Sourasky Medical Center,

Tel Aviv, Israel

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Thomas Pieber, MD

    Medical University of Graz

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Andrea Berghofer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 11, 2011

First Posted

December 29, 2011

Study Start

July 1, 2011

Primary Completion

July 1, 2012

Last Updated

December 29, 2011

Record last verified: 2011-12

Locations