Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)
AIR
1 other identifier
interventional
74,766
1 country
1
Brief Summary
Switching from intravenous application of antiinfective agents to oral therapy is often performed late including high costs and risk of complications. This study will investigate the impact of displayed reminders in the electronic patient chart after 60h of intravenous therapy with an antiinfective agent.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2012
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 15, 2011
CompletedFirst Posted
Study publicly available on registry
December 26, 2011
CompletedStudy Start
First participant enrolled
January 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2012
CompletedDecember 19, 2013
December 1, 2013
11 months
November 15, 2011
December 18, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
duration of intravenous antiinfective therapy until switching
1 year
Secondary Outcomes (5)
costs (per year, per day and patient)
1 year
defined daily doses (per 100 days)
1 year
duration of hospitalization
1 year
ratio of narrow to broad-spectrum antibiotics
1 year
requests for consultations
1 year
Study Arms (2)
electronic reminders
ACTIVE COMPARATORBehavioral: Early switching from intravenous to oral antiinfective agents due to electronic reminders
no electronic reminders
NO INTERVENTIONBehavioral: Early switching from intravenous to oral antiinfective agents without computerized decision support
Interventions
Behavioral: Early switching from intravenous to oral antiinfective agents due to electronic reminders
Eligibility Criteria
You may qualify if:
- all in-patients in treatment with an intravenous antiinfective for \>60h,
- hospitalized in a ward with computerized physician order entry (cpoe)
You may not qualify if:
- outpatients,
- ward without cpoe,
- no intravenous antiinfective treatment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Hospital Zurich, Center for Clinical Research
Zurich, Canton of Zurich, 8091, Switzerland
Related Publications (1)
Beeler PE, Kuster SP, Eschmann E, Weber R, Blaser J. Earlier switching from intravenous to oral antibiotics owing to electronic reminders. Int J Antimicrob Agents. 2015 Oct;46(4):428-33. doi: 10.1016/j.ijantimicag.2015.06.013. Epub 2015 Jul 21.
PMID: 26293470DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Juerg Blaser, Professor
University Hospital Zurich, Center for Clinical Research
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 15, 2011
First Posted
December 26, 2011
Study Start
January 1, 2012
Primary Completion
December 1, 2012
Study Completion
December 1, 2012
Last Updated
December 19, 2013
Record last verified: 2013-12