NCT01498146

Brief Summary

The SURPRISE study investigates atrial fibrillation(AFIB) in patients with a previous unexplained stroke. It uses long term monitoring of the heart of up to three years, searching for paroxysmal atrial fibrillation(PAF) otherwise undetected in this population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
85

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2010

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2010

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

December 21, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 23, 2011

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2013

Completed
Last Updated

January 28, 2021

Status Verified

January 1, 2021

Enrollment Period

3.5 years

First QC Date

December 21, 2011

Last Update Submit

January 26, 2021

Conditions

Stroke

Keywords

cryptogenic strokeatrial fibrillationlongterm monitoringloop recorder

Eligibility Criteria

Age18 Months+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

the patients are included from the investigators stroke unit and day clinic

You may qualify if:

  • Computerized Tomography (CT) or Magnetic resonance imaging (MRI) verified cryptogenic stroke or TIA;
  • \> 18 years of age,
  • the ability to provide a written consent

You may not qualify if:

  • prior or known AFIB
  • AF found during work up including 24 hour telemetric monitoring.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bispebjerg Hospital, University Hospital of Copenhagen, dept of Neurology

Copenhagen, DK-2400, Denmark

Location

Related Publications (1)

  • Biering-Sorensen T, Christensen LM, Krieger DW, Mogelvang R, Jensen JS, Hojberg S, Host N, Karlsen FM, Christensen H. LA emptying fraction improves diagnosis of paroxysmal AF after cryptogenic ischemic stroke: results from the SURPRISE study. JACC Cardiovasc Imaging. 2014 Sep;7(9):962-3. doi: 10.1016/j.jcmg.2014.02.003. Epub 2014 Apr 9. No abstract available.

    PMID: 24726253DERIVED

MeSH Terms

Conditions

StrokeIschemic StrokeAtrial Fibrillation

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesArrhythmias, CardiacHeart DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Hanne Christensen, MD, PhD, DMSci

    University of Copenhagen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Research Professor, Consultant neurologist

Study Record Dates

First Submitted

December 21, 2011

First Posted

December 23, 2011

Study Start

April 1, 2010

Primary Completion

October 1, 2013

Study Completion

October 1, 2013

Last Updated

January 28, 2021

Record last verified: 2021-01

Locations

DK(1)