The Effect of Marketing Variable on Effect of Active Drugs
The Effect of Price and Marketing Variable on the Pain Controlling Effect of Active Drugs in a Clinical Trial.
1 other identifier
interventional
220
1 country
1
Brief Summary
The efficacy of the placebo effect has been proved in many prior studies by comparing the symptoms and measures of patients. Placebo has been proved to help in treating illnesses such as depression, stomach ulcer and chronic headaches. A Meta analysis checked 47 studies about placebo and showed great significance when a patient is treated with placebo pill, no active substance, just by activating conditioning and expectation mechanism in his body, thus providing to the healing process, and that is it's importance. In recent years studies established a relationship between marketing variables (such as price, label) to the efficacy of a product. In addition- a unique research run in 2008 showed a significant relationship between the marketing strategies and the efficacy of medication; more specifically, patients in this research experienced less (controlled) pain when treated with placebo medication introduced to them as more expensive than patients treated with placebo medication that was introduced to them as much cheaper. All patients were treated with the exact same medication. In the investigator's experiment the investigators design a laboratory experiment to determine if marketing factors could invoke the placebo effects described earlier. For the initial laboratory experiment, we decided to examine the difference in price, on the efficacy of an OTC analgesic through the mediation of low- voltage electrical pulses to the patient's wrist. The investigators study hypothesis is that marketing variables such as price and brand name will affect the therapeutic efficacy of an analgesic, i.e. a medicine will have greater influence when the patient is aware of its price compared to one who is not.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable pain
Started Jan 2012
Typical duration for not_applicable pain
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 15, 2011
CompletedFirst Posted
Study publicly available on registry
December 16, 2011
CompletedStudy Start
First participant enrolled
January 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2013
CompletedDecember 16, 2011
December 1, 2011
11 months
December 15, 2011
December 15, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
pain thresholds
Participants will rank their pain thresholds individually and subjectively for a series of pulses. Each participant will experience a series of pulses with random intensity. Pulse intensity will range within 30-90% of the participants maximal level.
1hour
Study Arms (5)
High price
ACTIVE COMPARATORLow price
ACTIVE COMPARATORLow price participants aware paying part
ACTIVE COMPARATORNo price
ACTIVE COMPARATORFree of charge
ACTIVE COMPARATORInterventions
Acetaminophen label as low price; participants aware they are paying part of the full price
Eligibility Criteria
You may qualify if:
- Healthy Volunteer participants will be between the ages of 18 and 65
You may not qualify if:
- Candidates who have had a history of cardiac problems, epilepsy, diabetes, or are pregnant will be excluded.
- Taking no pain medication at the time of the experiment.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Family Medicine, Hebrew University, JerusaelmIsrael
Jerusalem, 91120, Israel
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Amnon - Lahad, MD, MPH
Hebrew University, Jerusalem Israel
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 15, 2011
First Posted
December 16, 2011
Study Start
January 1, 2012
Primary Completion
December 1, 2012
Study Completion
June 1, 2013
Last Updated
December 16, 2011
Record last verified: 2011-12