NCT01491750

Brief Summary

The purpose of this mixed methods pilot study is to produce preliminary data for a randomized, placebo-controlled trial testing a biobehavioral model of the effects of guided imagery on outcomes of total knee replacement surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Jun 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

October 4, 2011

Completed
2 months until next milestone

First Posted

Study publicly available on registry

December 14, 2011

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
Last Updated

January 6, 2014

Status Verified

January 1, 2014

Enrollment Period

2.5 years

First QC Date

October 4, 2011

Last Update Submit

January 2, 2014

Conditions

Keywords

SURGERYTOTAL JOINT REPLACEMENTTOTAL KNEE REPLACEMENTGUIDED IMAGERYCOMPLEMENTARY AND ALTERNATIVE THERAPY

Outcome Measures

Primary Outcomes (1)

  • function

    WOMAC AND SF-36

    6 months

Study Arms (2)

GUIDED IMAGERY

EXPERIMENTAL
Behavioral: GUIDED IMAGERY

AUDIO BOOK

PLACEBO COMPARATOR
Behavioral: PLACEBO

Interventions

GUIDED IMAGERYBEHAVIORAL

DAILY LISTENING TO A GUIDED IMAGERY CD FOR 2 WEEKS BEFORE AND 3 WEEKS AFTER SURGERY

GUIDED IMAGERY
PLACEBOBEHAVIORAL

DAILY LISTENING TO AN AUDIO BOOK SEGMENT FOR 2 WEEKS BEFORE AND 3 WEEKS AFTER SURGERY

AUDIO BOOK

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • scheduled for a single TKR
  • attendance at the hospital joint replacement class
  • ability to speak, read, and write English -

You may not qualify if:

  • current or planned use of guided imagery
  • history of previous total joint replacement
  • current enrollment in another clinical studY
  • current treatment in a pain management program
  • current diagnosis of immune disorders (e.g., rheumatoid arthritis, organ transplant, cancer, HIV, SLE)
  • use of immune altering medications in past month
  • comorbidities that would limit participation in study procedures or postoperative rehabilitation and/or impair recovery (e.g., psychosis; sensory, cognitive, neurologic or motor impairment
  • vision or hearing deficits
  • lymphedema
  • morbid obesity \[BMI \> 40\])
  • reported diagnosis of anemia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Crystal Clinic Orthopaedic Center

Akron, Ohio, 44310, United States

Location

MeSH Terms

Conditions

Osteoarthritis

Interventions

Imagery, Psychotherapy

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • ANN F JACOBSON, PHD

    Kent State University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, College of Nursing

Study Record Dates

First Submitted

October 4, 2011

First Posted

December 14, 2011

Study Start

June 1, 2011

Primary Completion

December 1, 2013

Study Completion

December 1, 2013

Last Updated

January 6, 2014

Record last verified: 2014-01

Locations