NCT01490606

Brief Summary

A. Background. Patients with osteoarthritis (OA) of the knee, suffer from a combination of pain, stiffness, joint instability, swelling and muscles weakness. This leads to decrease in quality of life, Active Daily living (ADL) and increase of medical services consumption in the community. OA of the knee, Is one of the world's common musculoskeletal disorder (18% among women and 10% among men). 80% of patients with OA of the knee suffer from decrease in mobility and 20% of them suffer an inability to perform everyday activities. Physical therapy training includes exercises for OA patients (Mild to Severe degree) is the cornerstone of non medicinal treatment. This training aimed to pain reduction, improved functioning and participation in family and working social life. Physical training with exercises can enhance physical capabilities such as: muscular strength, range of motion, balance, proprioception and cardiovascular performance. Other benefits are improving mobility, reducing risk of falls and body weight and improvement in psychological condition. B. Purpose The purpose of this research is to check the effectiveness of treatment in the framework of "knee Osteoarthritis project" compared to conventional Physical therapy in physical functioning, pain and quality of life scales, among patients over the age of 60 who suffer from OA of the knee . C. Research method A comparative non blinded, clinical trial will be conducted. This research will include 60 independent patients divided into equal groups: Intervention group will be trained in "knee Osteoarthritis project" (in which patients receive 6 individual treatments and 6 Group treatments). Control group will be treated with conventional physical therapy, which includes 12 individual treatments. Effect of the treatment will be evaluated by: 1. WOMAC questionnaire- used to evaluate function and pain. 2. EQ-5D questionnaire for evaluating the quality of life. 3. Time up and go test- a Common functional test. This Questionnaires and test will be Performed before and after the study. D. Study hypothesis Physical therapy treatment within the framework of "knee Osteoarthritis project" is favor than the treatment of the conventional Physical therapy. Therefore the investigators expect much improvement in terms of pain, physical functioning and quality of life among intervention group compared to control groups.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2012

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 8, 2011

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 13, 2011

Completed
19 days until next milestone

Study Start

First participant enrolled

January 1, 2012

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2012

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

March 5, 2012

Status Verified

March 1, 2012

Enrollment Period

8 months

First QC Date

December 8, 2011

Last Update Submit

March 2, 2012

Conditions

Outcome Measures

Primary Outcomes (3)

  • Time up and go test

    Patient sits on a chair with handles. by order "go", patient will stand up and walk 3 meters forward circle a Conus and return to the chair. a time watch will count time.

    On the first week- first session of PT and on last session- 12 weeks Average

  • WOMAC questionaire

    On the first week- first session of PT and on last session- 12 weeks Average

  • EQ-5D questionaire

    On the first week- first session of PT and on last session- 12 weeks Average

Secondary Outcomes (1)

  • Body Mass index

    Up to the first week- on the first session of PT

Study Arms (2)

knee OA project

EXPERIMENTAL

12 sessions of PT, 6 INDIVIDUAL AND 6 GROUP TREATMENTS

Other: knee OA projectOther: conventional PT

conventional PT

NO INTERVENTION

Interventions

physical therapy in "OA Knee project", total of 12 sessions, 6 group therapies amd 6 one on one therapy.

knee OA project

12 SESSIONS OF CONVENTIONAL PHYSICAL THERAPY

knee OA project

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • + years old independent men and women,who suffer from OA in the knee and was referred to Physiotherapy.
  • ability to write and read properly in Hebrew

You may not qualify if:

  • OA secondary to systematic disease (Rheumatoid arthritis)
  • steroids injections to the knee in the past 3 months.
  • orthopaedic surgery to lower limbs.
  • neurological deficit.
  • symptomatic OA in the hip or ankle

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clalit Health Service

Jerusalem, Israel, 97802, Israel

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Yair Barzilai, M.D.

    Clalit health service, Israel

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Shimi Fatal, BPT

CONTACT

Yair barzilai, M.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
physical therapist

Study Record Dates

First Submitted

December 8, 2011

First Posted

December 13, 2011

Study Start

January 1, 2012

Primary Completion

September 1, 2012

Study Completion

December 1, 2012

Last Updated

March 5, 2012

Record last verified: 2012-03

Locations