NCT01487850

Brief Summary

On the basis of 2 cases of immunologically-induced lung disease in 2 saxophonists, the investigators supposed that wind reed instruments could be contaminated with molds. The investigators led a study on 40 musicians playing a wind reed instrument to analyze instruments' fungal contamination and its immunological and clinical consequences for musicians.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started May 2007

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2007

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2007

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2007

Completed
4.2 years until next milestone

First Submitted

Initial submission to the registry

December 6, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 8, 2011

Completed
Last Updated

December 9, 2011

Status Verified

December 1, 2011

Enrollment Period

1 month

First QC Date

December 6, 2011

Last Update Submit

December 8, 2011

Conditions

Immunologically-induced Lung DiseaseHypersensitivity Pneumonitis

Keywords

wind instrumentsmoldshypersensitivity pneumonitisfungal contamination of wind instrumentsspecific antibodies against molds in musicians' seramusicians

Interventions

blood sampleBIOLOGICAL

blood sample in each musician to search for specific antibodies against molds isolated from instruments

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • must be 18 year old or more
  • must play a wind reed instrument (saxophone, clarinet, bassoon or oboe) one hour per week or more

You may not qualify if:

  • refuse to sign consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier Universitaire Saint Jacques

Besançon, Franche Comté, 25000, France

Location

Related Publications (2)

  • Lodha S, Sharma OP. Hypersensitivity pneumonitis in a saxophone player. Chest. 1988 Jun;93(6):1322. doi: 10.1378/chest.93.6.1322. No abstract available.

    PMID: 3371127RESULT

  • Metzger F, Haccuria A, Reboux G, Nolard N, Dalphin JC, De Vuyst P. Hypersensitivity pneumonitis due to molds in a saxophone player. Chest. 2010 Sep;138(3):724-6. doi: 10.1378/chest.09-2991.

    PMID: 20822994RESULT

MeSH Terms

Conditions

Alveolitis, Extrinsic Allergic

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Lung Diseases, InterstitialLung DiseasesRespiratory Tract DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Purpose
DIAGNOSTIC
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Doctor, Lung specialist, Principal Investigator

Study Record Dates

First Submitted

December 6, 2011

First Posted

December 8, 2011

Study Start

May 1, 2007

Primary Completion

June 1, 2007

Study Completion

October 1, 2007

Last Updated

December 9, 2011

Record last verified: 2011-12

Locations

FR(1)